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Merck
CN

740705

Sigma-Aldrich

聚(乙二醇)甲醚2-(十二烷基硫基硫代羰基硫基)-2-甲基丙酸酯

average Mn 1,100

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别名:
PEG DDMAT macroCTA, 甲氧基聚(环氧乙烷)-2-(十二烷基硫基硫代羰基硫基)-2-甲基丙酸酯
UNSPSC代码:
12162002
NACRES:
NA.23

形式

liquid
semisolid
solid

分子量

average Mn 1,100

反应适用性

reagent type: chemical modification reagent
reaction type: Polymerization Reactions

转变温度

Tm 22-27 °C

PDI

≤1.1

Ω端

DDMAT

α端

methoxy

聚合物结构设计

shape: linear
functionality: monofunctional

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一般描述

Need help choosing the correct RAFT Agent? Please consult the RAFT Agent to Monomer compatibility table.

Molecular weight: PEG Average Mn ~750 kDa; n ~17

应用

RAFT agent for controlled radical polymerization; especially suited for the polymerization of styrene; acrylate and acrylamide monomers to make lithographically and biologically important PEG-block copolymers. Chain Transfer Agent (CTA)

象形图

Exclamation mark

警示用语:

Warning

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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RAFT Agent Design and Synthesis
Keddie, D. J.; et al.
Macromolecules, 45, 5321-5342 (2012)
Massimo Benaglia et al.
Journal of the American Chemical Society, 131(20), 6914-6915 (2009-05-01)
The polymerization of most monomers that are polymerizable by radical polymerization can be controlled by the reversible addition-fragmentation chain transfer (RAFT) process. However, it is usually required that the RAFT agent be selected according to the types of monomer being

商品

Reversible addition–fragmentation chain transfer (RAFT) polymerization is rapidly moving to the forefront in construction of drug and gene delivery vehicles.

The modification of biomacromolecules, such as peptides and proteins, through the attachment of synthetic polymers has led to a new family of highly advanced biomaterials with enhanced properties.

Micro review of reversible addition/fragmentation chain transfer (RAFT) polymerization.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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实验方案

We present an article about RAFT, or Reversible Addition/Fragmentation Chain Transfer, which is a form of living radical polymerization.

We presents an article featuring procedures that describe polymerization of methyl methacrylate and vinyl acetate homopolymers and a block copolymer as performed by researchers at CSIRO.

Polymerization via ATRP procedures demonstrated by Prof. Dave Haddleton's research group at the University of Warwick.

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