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经验公式(希尔记法):
C27D3H41O3
化学文摘社编号:
分子量:
419.65
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
200-578-6
MDL number:
产品名称
1α,25-二羟基维生素D3 (6,19,19-d3) 溶液, 50 μg/mL in ethanol, 97 atom % D, 96% (CP)
InChI key
GMRQFYUYWCNGIN-POLIPXRRSA-N
InChI
1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1/i2D2,11D
SMILES string
[2H]/C([2H])=C1[C@@H](O)C[C@H](O)CC\1=C([2H])\C=C2/CCC[C@]3(C)[C@H](CC[C@@H]23)[C@H](C)CCCC(C)(C)O
isotopic purity
97 atom % D
assay
96% (CP)
form
solution
concentration
50 μg/mL in ethanol
technique(s)
mass spectrometry (MS): suitable
color
colorless
mp
-144.0 °C
application(s)
detection
mass shift
M+3
storage temp.
−20°C
Quality Level
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Application
1α,25-二羟基维生素 D3 (6,19,19-d3) 可用作稳定的同位素内标物,用于通过质谱获得特定生物样品的准确数据。
General description
1α,25-二羟基维生素 D3 [1,25(OH)2D3]又称骨化三醇,在人类的钙和磷代谢中起一定作用。它还调节胰岛素分泌并诱导细胞分化。
1α,25-二羟基维生素D3 (6,19,19-d3) 是氘化的维生素D3,其中的 C-6和C-19质子被氘取代。
1α,25-二羟基维生素D3 (6,19,19-d3) 是氘化的维生素D3,其中的 C-6和C-19质子被氘取代。
Packaging
1 mL,安瓿瓶装
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 1
flash_point_f
57.2 °F - closed cup
flash_point_c
14.0 °C - closed cup
法规信息
危险化学品
此项目有
Jianqiong Zheng et al.
Frontiers in pharmacology, 11, 97-97 (2020-03-19)
Metabolic syndrome is a disorder of energy use and storage, which is characterized by central obesity, dyslipidemia, and raised blood pressure and blood sugar levels. Maternal 25-hydroxyvitamin D deficiency is known to cause metabolic changes, chronic disease, and increased adiposity
The emerging role of vitamin D3 in women′s health
Khadilkar, SS
The Journal of Obstetrics and Gynecology of India, 63(2), 147?150-147?150 (2013)
Xinzhu Liu et al.
Burns & trauma, 8, tkaa042-tkaa042 (2021-01-28)
Gut ischemia and hypoxia post severe burn leads to breakdown of intestinal epithelial barrier and enteric bacterial translocation (EBT), resulting in serious complications, such as systemic inflammatory response syndrome, sepsis and multiple organ failure. Cystic fibrosis transmembrane conductance regulator (CFTR)
Vitamin D3: a helpful immuno-modulator
Di R, et al.
Immunology, 134(2), 123-139 (2011)
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