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质量水平
检测方案
98% (CP)
形式
solution
浓度
50 μg/mL in ethanol
技术
mass spectrometry (MS): suitable
颜色
colorless
应用
detection
储存温度
−20°C
SMILES字符串
C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C
InChI
1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1
InChI key
JWUBBDSIWDLEOM-DTOXIADCSA-N
基因信息
human ... VDR(7421)
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一般描述
25-Hydroxyvitamin D3 (calcifediol) is a prohormone produced via hydroxylation of vitamin D3 (cholecalciferol) in the liver. It is a precursor for the synthesis of calcitriol {1,25-dihydroxyvitamin D3 or [1,25(OH)2D3]}. It is also used as a biomarker to determine the status of vitamin D in the body.
应用
This product may be used as an analytical standard.
包装
1 mL in ampule
警示用语:
Danger
危险声明
危险分类
Eye Irrit. 2 - Flam. Liq. 2
WGK
WGK 1
闪点(°F)
57.2 °F
闪点(°C)
14.0 °C
法规信息
新产品
The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 57(3), 263-269 (2015-08-25)
With the increasing burden of noncommunicable disease, adolescence is viewed as an opportune time to prevent the onset of certain behaviors and promote healthy states. Although adolescents comprise a considerable portion of Saudi Arabia's population, they have received insufficient attention
Therapeutic drug monitoring, 37(6), 733-744 (2015-04-09)
In view of the large variability on therapeutic response and the multiple factors associated to tamoxifen (TAM) metabolic activation, this study aimed to evaluate the effect of CYP2D6 and CYP3A4 phenotypes, drug interactions, and vitamin D exposure on TAM metabolism
Molecular nutrition & food research, 59(8), 1513-1523 (2015-03-27)
The impact of L-ascorbic acid (L-AA) on the chemokinesis (CK) and chemotaxis (CT) of HL-60 cells and polymorphonuclear cells (PMN) was investigated. HL-60 cells were differentiated with DMSO, retinoic acid (RA), vitamin D, or L-AA. Chemokinesis and chemotaxis of differentiated
25-Hydroxyvitamin D3, the prohormone of 1, 25-dihydroxyvitamin D3, inhibits the proliferation of primary prostatic epithelial cells
Cancer Epidemiology, Biomarkers & Prevention, 9(3), 265-270 (2000)
Quantification of circulating 25-hydroxyvitamin D by liquid chromatography-tandem mass spectrometry
The Journal of Steroid Biochemistry and Molecular Biology, 121(3-5), 565-573 (2010)
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