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Merck
CN

73861

Sigma-Aldrich

N-亚硝基二乙胺

≥99.0% (GC)

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别名:
二乙基亚硝胺
线性分子式:
(C2H5)2NNO
CAS号:
分子量:
102.14
Beilstein:
1744991
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

≥99.0% (GC)

形式

liquid

IVD

for in vitro diagnostic use

bp

177 °C (lit.)

密度

0.95 g/mL (lit.)

SMILES字符串

CCN(CC)N=O

InChI

1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3

InChI key

WBNQDOYYEUMPFS-UHFFFAOYSA-N

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应用

N-亚硝基二乙胺可作为反应物用于合成:
  • 在 HCl 环境下通过可见光诱导的光加成反应从烯烃中生成α-氨基肟衍生物
  • 在二氯甲烷环境下从金属卟啉生成二乙基亚硝胺金属卟啉络合物

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B

WGK

WGK 3

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Changyu Zhu et al.
Journal of hepatology, 74(3), 613-626 (2020-10-11)
The hepatocyte Notch pathway is a pathogenic factor in non-alcoholic steatohepatitis (NASH)-associated fibrosis, but its role in hepatocellular carcinoma (HCC) is less well defined. Herein, we aimed to characterize the molecular and clinical features of Notch-active human HCC, and to
Li Chen et al.
Inorganic chemistry, 37(18), 4677-4688 (2001-10-24)
Diethylnitrosamine reacts with [(TPP)Fe(THF)(2)]ClO(4) (TPP = 5,10,15,20-tetraphenylporphyrinato dianion) in toluene to generate the bis-nitrosamine complex, [(TPP)Fe(Et(2)NNO)(2)]ClO(4), in 96% isolated yield. The related [(TTP)Fe(Et(2)NNO)(2)]SbF(6) (TTP = 5,10,15,20-tetra-p-tolylporphyrinato dianion) complex is prepared in 70% isolated yield via a similar reaction in CH(2)Cl(2).
Dilip V Patil et al.
Organic letters, 23(8), 3105-3109 (2021-04-02)
The generation of aminium radical cation species from N-nitrosoamines is disclosed for the first time through visible-light excitation at 453 nm. The developed visible-light-promoted photoaddition reaction of N-nitrosoamines to alkenes was combined with the o-NQ-catalyzed aerobic oxidation protocol of amines
Koichi Fujisawa et al.
PloS one, 10(6), e0129950-e0129950 (2015-06-25)
Maid is a helix-loop-helix protein that is involved in cell proliferation. In order to further elucidate its physiological functions, we studied Maid activity in two small fish model systems. We found that Maid expression was greatest in zebrafish liver and
L Verna et al.
Pharmacology & therapeutics, 71(1-2), 57-81 (1996-01-01)
N-Nitrosodiethylamine (NDEA) is DNA reactive after bioactivation and produces tumors in every animal species tested. Bioactivation is effected by several P450 isozymes including CYP2E1, which is ethanol inducible. Tumor formation in rat liver was proportional to O4-ethyldeoxythymidine formation in DNA

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