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产品名称
Fmoc-Pro-Bt, 95%
方案
95%
表单
solid
mp
163-168 °C
应用
peptide synthesis
官能团
Fmoc
储存温度
2-8°C
SMILES字符串
O=C(OCC1c2ccccc2-c3ccccc13)N4CCC[C@H]4C(=O)n5nnc6ccccc56
InChI
1S/C26H22N4O3/c31-25(30-23-13-6-5-12-22(23)27-28-30)24-14-7-15-29(24)26(32)33-16-21-19-10-3-1-8-17(19)18-9-2-4-11-20(18)21/h1-6,8-13,21,24H,7,14-16H2/t24-/m0/s1
InChI key
ZTDUGEKWIJHWKX-DEOSSOPVSA-N
应用
Benzotriazole amino acids, or aminoacylbenzotriazolides, are versatile reagents for synthesizing peptides as well as their mimetics and conjugates. Benzotriazole amino acids have been used for the preparation of diverse derivatives including:
- Polypeptidal benzotriazolides
- Peptidomimetics, such as aminoxypeptides, depsipeptides and heterocyclic peptidomimetics
- Tagged peptides and peptidomimetics, particularly those with fluorescent labels
- N, O, S, and C linked peptide conjugates
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Katritzky, A. R.; Angrish, P.; Todadze, E.
Synlett, 2392-2411 (2009)
Katritzky, A. R.; Narindoshvili, T.; Angrish, P.
Synthesis, 2013-2022 (2008)
Abdelmajeid, A.; Tala, S. R.; Amine, M. S.; Katritzky, A. R.
Synthesis, 2995-3005 (2011)
Hansen, F. K.; Beagle, L. K.; Todadze, E.; Katritzky, A. R.
Heterocycles, 515-526 (2012)
Alan R Katritzky et al.
The Journal of organic chemistry, 74(22), 8690-8694 (2009-10-17)
N-(Pg-alpha-aminoxy acids) 1a-g are converted to N-(Pg-alpha-aminoxyacyl)benzotriazoles 2a-g, which react under mild conditions with amines, alpha-amino acids/alpha-dipeptides, and alpha-aminoxy acids to give aminoxyacyl amides 3a-g, (3e+3e'), and (3g+3g'), aminoxy hybrid peptides 4a-h, (4a+4a'), 6a-d, 9a-e, (9a+9a'), and (9b+9b'), and alpha-aminoxy
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