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Merck
CN

73340

5-硝基-2-糠醛半卡巴腙

≥97.0% (HPLC)

别名:

5-硝基-2-呋喃甲醛半卡腙, NFZ, 呋喃西林, 硝呋醛

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经验公式(希尔记法):
C6H6N4O4
化学文摘社编号:
分子量:
198.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-443-1
Beilstein/REAXYS Number:
86403
MDL number:
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产品名称

5-硝基-2-糠醛半卡巴腙, ≥97.0% (HPLC)

InChI

1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+

InChI key

IAIWVQXQOWNYOU-FPYGCLRLSA-N

SMILES string

NC(=O)N\N=C\c1ccc(o1)[N+]([O-])=O

assay

≥97.0% (HPLC)

form

powder

mp

242-244 °C (lit.)

functional group

amine
nitro

Quality Level

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Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

General description

Molecules of 5-nitro-2-furaldehyde semicarbazone are linked via bifurcated hydrogen bonds. Its crystal structure has been studied. It is reported to induce mammary fibroadenomas in Holtzman female rats and can be subcutaneously transplanted into male and female newborn Holtzman rats. Chemotheraupetic potential of 5-nitro-2-furaldehyde semicarbazone has been evaluated. 5-Nitro-2-furaldehyde semicarbazone is a synthetic nitrofuran derivative, having good bacteriostatic and bactericidal properties, with an antibacterial action against a number of gram-negative and gram-positive microorganisms. In Vitro toxicity of 5-nitro-2-furaldehyde semicarbazone has been investigated in hamster cells.

pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1 - STOT RE 2

target_organs

male reproductive organs

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

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5-Nitro-2-furaldehyde semicarbazone.
Olszak TA, et al.
Acta Crystallographica Section C, Structural Chemistry, 50(6), 948-950 (1994)
Transplantable rat mammary tumors induced by 5-nitro-2-furaldehyde semicarbazone and by formic acid 2-[4-(5-nitro-2-furyl)-2-thiazolyl] hydrazide.
E Ertürk et al.
Cancer research, 30(5), 1409-1412 (1970-05-01)
The chemotherapeutic properties of 5-nitro-2-furaldehyde semicarbazone (furacin).
M C DODD
The Journal of pharmacology and experimental therapeutics, 86, 311-323 (1946-04-01)
Nitrofurans as radiosensitizers of hypoxic mammalian cells.
J D Chapman et al.
Cancer research, 32(12), 2616-2624 (1972-12-01)
Sonoelectrodeposition of gold nanorods at a gold surface-Application for electrocatalytic reduction and determination of nitrofurazone.
Rahi A, et al.
Sensors and Actuators B, Chemical (2014)

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