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Merck
CN

724858

Sigma-Aldrich

聚(N-异丙基丙烯酰胺-co-甲基丙烯酸)

methacrylic acid 10 mol %, Mn 60,000

别名:

功能化聚(N-异丙基丙烯酰胺), 功能化聚丙烯酰胺, 聚(N-异丙基丙烯酰胺), 聚(NIPAM-co-MAA), 聚丙烯酰胺

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About This Item

线性分子式:
(C6H11NO)m (C4H6O2)n
MDL编号:
UNSPSC代码:
12162002
NACRES:
NA.23

表单

solid

质量水平

分子量

Mn 60,000

组成

methacrylic acid, 10 mol %

mp

>300 °C

Mw/Mn

≤2.5

SMILES字符串

N(C(C)C)C(=O)C=C.OC(=O)C(=C)C

InChI

1S/C6H11NO.C4H6O2/c1-4-6(8)7-5(2)3;1-3(2)4(5)6/h4-5H,1H2,2-3H3,(H,7,8);1H2,2H3,(H,5,6)

InChI key

BGJOTKHBFYMJST-UHFFFAOYSA-N

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应用

智能溶胀/塌陷共聚物,可用作温度和pH敏感材料。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

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Ana M Díez-Pascual et al.
Journal of colloid and interface science, 347(1), 79-89 (2010-04-14)
The confinement of polyelectrolyte multilayers of poly-L-lysine (PLL)/poly-L-glutamic acid (PGA) and chitosan (CHIT)/dextran sulfate (DEX) onto soft and porous thermoresponsive poly(N-isopropylacrylamide-co-methacrylic acid) (P(NiPAM-co-MAA)) microgel was studied by dynamic light scattering (DLS) and electrophoretic measurements. DLS demonstrates an "odd-even" effect in
Weitai Wu et al.
Biosensors & bioelectronics, 25(12), 2603-2610 (2010-05-18)
A new class of optical glucose nanobiosensors with high sensitivity and selectivity at physiological pH is described. To construct these glucose nanobiosensors, the fluorescent CdS quantum dots (QDs), serving as the optical code, were incorporated into the glucose-sensitive poly(N-isopropylacrylamide-acrylamide-2-acrylamidomethyl-5-fluorophenylboronic acid)
Eva Díez-Peña et al.
AAPS PharmSciTech, 5(2), e33-e33 (2005-03-12)
A series of poly[(N-isopropylacrylamide)-co-(methacrylic acid)] (P[(N-iPAAm)-co-(MAA)]) hydrogels was investigated to determine the composition that exhibits a better pH-modulated release of diltiazem hydrochloride (DIL.HCl). For this purpose hydrogel slabs were loaded with DIL.HCl by the immersion method, and its release under
Sabrina Schmidt et al.
Langmuir : the ACS journal of surfaces and colloids, 27(16), 9801-9806 (2011-07-09)
Charged poly(N-isopropylacrylamide-co-methacrylic acid) [P(NiPAM-co-MAA)] microgels can stabilize thermo- and pH-sensitive emulsions. By placing charged units at different locations in the microgels and comparing the emulsion properties, we demonstrate that their behaviors as emulsion stabilizers are very different from molecular surfactants
J Moselhy et al.
Journal of biomaterials science. Polymer edition, 11(2), 123-147 (2000-03-16)
The pH- and temperature-responsive poly(N-isopropylacrylamide-co-methacrylic acid) (PNIPAm/MAA) nanoparticles are of potential application in targeted drug delivery. Their responsive properties in the presence of human serum albumin were investigated using dynamic light scattering (DLS), protein assay, and electron spin resonance (ESR)

商品

Poly(N-isopropylacrylamide), or PNIPAM, is a stimuli-responsive polymer that responds to changes in pH and temperature and has a LCST around 32 C.

组织工程已成为治疗受损或患病的器官和组织(例如血管和尿囊)的关键治疗工具。

Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.

By altering the physicochemical properties, smart or intelligent drug delivery systems can be designed to deliver therapeutic molecules on-demand. Learn more about the application of stimuli-responsive materials in drug delivery.

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