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Merck
CN

719714

2,6-二异丙基苯硼酸

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经验公式(希尔记法):
C12H19BO2
化学文摘社编号:
分子量:
206.09
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352103
MDL number:
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InChI

1S/C12H19BO2/c1-8(2)10-6-5-7-11(9(3)4)12(10)13(14)15/h5-9,14-15H,1-4H3

SMILES string

CC(C)c1cccc(C(C)C)c1B(O)O

InChI key

UPXGMXMTUMCLGD-UHFFFAOYSA-N

form

solid

mp

167-172 °C

Application

2,6-Diisopropylphenylboronic acid can be used as a reactant:
  • In the Pd-catalyzed Suzuki-Miyaura cross-coupling reactions.
  • To synthesis potent propargyl-based inhibitors of the Cryptosporidium dihydrofolate reductase (DHFR) enzyme.
  • To prepare boralumoxane applicable in the activation of zirconocene catalyst for the polymerization ethene.

存储类别

11 - Combustible Solids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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David B Bolstad et al.
Journal of medicinal chemistry, 51(21), 6839-6852 (2008-10-07)
Cryptosporidiosis is an emerging infectious disease that can be life-threatening in an immune-compromised individual and causes gastrointestinal distress lasting up to 2 weeks in an immune-competent individual. There are few therapeutics available for effectively treating this disease. We have been
Catalytic hydrosilylation of alkenes by iron complexes containing terpyridine derivatives as ancillary ligands
Kamata K, et al.
Organometallics, 31(10), 3825-3828 (2012)
Synthesis and structural characterisation of a boralumoxane capable of activating a zirconocene ethene polymerisation catalyst
Richter B, et al.
Chemical Communications (Cambridge, England), (14), 1286-1287 (2001)

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