形式
liquid
质量水平
浓度
1 M in methylene chloride
折射率
n20/D 1.423
密度
1.294 g/mL at 25 °C
SMILES字符串
CC(Cl)=O
InChI
1S/C2H3ClO/c1-2(3)4/h1H3
InChI key
WETWJCDKMRHUPV-UHFFFAOYSA-N
应用
Acetyl chloride (AcCl) can be used as:
- An acylating reagent to prepare useful key intermediates in organic synthesis.
- A reagent to convert oxathioacetals and dithioacetals into corresponding carbonyl compounds in the presence of sodium nitrite.
- An activating or acylating reagent in solid-phase organic synthesis.
- A reagent to prepare various alkyl and aryl tetrahydropyranyl ethers from corresponding alcohols.
警示用语:
Danger
危险分类
Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
靶器官
Central nervous system
WGK
WGK 2
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
危险化学品
Selective synthesis of spirooxindoles via a two-step reaction of N-phenacylpyridinium bromide, 1, 3-indanedione and N-alkylisations
Organic & Biomolecular Chemistry, 17(16), 3978-3983 (2019)
New phenylfluorenyl based linkers for solid phase synthesis
Tetrahedron Letters, 41(47), 9037-9042 (2000)
Acetyl chloride-mediated mild and chemoselective attachment and removal of tetrahydropyranyl (THP) group
Bulletin of the Korean Chemical Society,, 28(1), 103-107 (2007)
Solid phase synthesis of styrylquinazolinones
Tetrahedron Letters, 41(13), 2051-2054 (2000)
A highly efficient procedure for regeneration of carbonyl groups from their corresponding oxathioacetals and dithioacetals using sodium nitrite and acetyl chloride in dichloromethane
Synlett, 2003(03), 0377-0381 (2003)
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