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Merck
CN

691534

Sigma-Aldrich

4-硝基吲哚-3-甲醛

97%

别名:

3-甲酰基-4-硝基吲哚

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About This Item

经验公式(希尔记法):
C9H6N2O3
CAS号:
分子量:
190.16
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

方案

97%

表单

solid

mp

189-193 °C

官能团

aldehyde
nitro

SMILES字符串

[O-][N+](=O)c1cccc2[nH]cc(C=O)c12

InChI

1S/C9H6N2O3/c12-5-6-4-10-7-2-1-3-8(9(6)7)11(13)14/h1-5,10H

InChI key

CGXVTWQTGQAMMX-UHFFFAOYSA-N

应用

  • reactant in synthesis of tryptophan dioxygenase inhibitors as potential anticancer immunomodulators
  • reactant in synthesis of structural analogs of thaxtomin
  • reactant in preparation of chromophores related to gold fluorescent protein
  • reactant in preparation of brassinin and gramine derivatives

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

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分析证书(COA)

Lot/Batch Number

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访问文档库

Prueger, Birgit; Bach, Thorsten.
Synthesis, 7, 1103-1103 (2007)
Tetrahedron, 46, 6085-6085 (1990)
Molesworth, P., P.; et al.
Australian Journal of Chemistry, 63, 813-813 (2010)
Yamada, F.; et al.
Heterocycles, 36, 2783-2783 (1993)
Eduard Dolusić et al.
Journal of medicinal chemistry, 54(15), 5320-5334 (2011-07-06)
Tryptophan catabolism mediated by indoleamine 2,3-dioxygenase (IDO) is an important mechanism of peripheral immune tolerance contributing to tumoral immune resistance. IDO inhibition is thus an active area of research in drug development. Recently, our group has shown that tryptophan 2,3-dioxygenase

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