所有图片(1)
About This Item
经验公式（希尔记法）:
C16H12N2O7
CAS号:
分子量:
344.28
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.22
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质量水平
方案
97%
表单
solid
mp
173-177 °C
官能团
anhydride
ester
nitro
SMILES字符串
Cc1cccc(c1C(=O)OC(=O)c2c(C)cccc2[N+]([O-])=O)[N+]([O-])=O
InChI
1S/C16H12N2O7/c1-9-5-3-7-11(17(21)22)13(9)15(19)25-16(20)14-10(2)6-4-8-12(14)18(23)24/h3-8H,1-2H3
InChI key
YEKPNMQQSPHKBP-UHFFFAOYSA-N
一般描述
2-甲基-6-硝基苯甲酸酐可用作酰胺、内酯、酯和肽合成中的偶联促进剂。
应用
2-甲基-6-硝基苯甲酸酐可用于：
- 作为多功能的内酯化试剂用于制备各种大环内酯天然产物和内酯。
- 作为反应促进剂采用相应的胺和羧酸合成羧酰胺衍生物。
- GRP78 抑制剂 prunustatin A、抗真菌化合物 (3R,16E,20E,23R)-(−)-eushearilide 和防肥胖药四氢利泼斯汀的全合成。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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[structure: see text] An effective method for the total synthesis of 2-hydroxy-24-oxooctacosanolide, a defensive salivary secretion of the African termite Pseudacanthotermes spiniger, has been developed. The key lactonization to form a 29-membered ring lactone core is performed using 2-methyl-6-nitrobenzoic anhydride
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A new highly sensitive analytical method was developed to investigate the in vivo metabolism of albiflorin, one of the most principal components in traditional Chinese medicine. After hydrolyzation with sulfatase, the main metabolites paeonilactone A and paeonilactone B of paeoniflorin
The effective use of substituted benzoic anhydrides for the synthesis of carboxamides
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Tetrahedron, 60(21), 4729-4733 (2004)
A novel and efficient macrolactonization of ω-hydroxycarboxylic acids using 2-methyl-6-nitrobenzoic anhydride (MNBA)
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Tetrahedron Letters, 43(42), 7535-7539 (2002)
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