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Merck
CN

677418

羟基磷灰石

nanopowder, <200 nm particle size (BET), ≥97%, synthetic

别名:

磷酸钙 三元, 三碱基磷酸钙, 氢氧磷灰石, 磷酸羟胺, 羟基磷酸钙

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关于此项目

线性分子式:
[Ca5(OH)(PO4)3]x
化学文摘社编号:
12167-74-7
分子量:
502.31
NACRES:
NA.23
PubChem Substance ID:
24885371
UNSPSC Code:
12352302
EC Number:
235-330-6
MDL number:
MFCD00010904
Assay:
≥97%
Form:
nanopowder
solid

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产品名称

羟基磷灰石, nanopowder, <200 nm particle size (BET), ≥97%, synthetic

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

assay

≥97%

form

nanopowder
solid

surface area

>9.4 m2/g

particle size

<200 nm (BET)

mp

1100 °C (lit.)

Quality Level

100

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相关类别

Application

纳米羟基磷灰石颗粒具有缓慢的原位生物降解、良好的骨导电性和骨诱导能力，可用于制备骨组织工程材料。

聚(4-苯乙烯磺酸钠)修饰的羟基磷灰石纳米颗粒可作为万古霉素的药物载体。羟基磷灰石纳米颗粒可控制支架植入体内后抗生素的释放。

多孔羟基磷灰石微球对重金属具有较高的吸附能力，可用于重金属污染水体的处理。

Features and Benefits

  • 生物活性和生物相容性
  • 机械强度好
  • 多孔结构
  • 骨传导和骨整合特性

General description

羟基磷灰石（HA）属于钙磷灰石家族， 在结构和化学成分上与天然骨相似。它可以 通过化学沉淀法、水热法、静电纺丝法和 自传播燃烧法等多种方法制备。由于其生物活性和生物相容性， 它被广泛用作骨再生的植入材料、 药物载体和基因传递系统。

Legal Information

Engi-Mat公司产品。

存储类别

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCZ9813
MKCZ5330
MKCZ0885
MKCX9459
MKCX8937

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Furqan A Shah
Scientific reports, 10(1), 16662-16662 (2020-10-09)
Various compositional parameters are derived using intensity ratios and integral area ratios of different spectral peaks and bands in the Raman spectrum of bone. The [Formula: see text]1-, [Formula: see text]2-,[Formula: see text]3-, [Formula: see text]4 PO43-, and [Formula: see
Sang-Soo Kim et al.
Biomaterials, 27(8), 1399-1409 (2005-09-20)
Biodegradable polymer/bioceramic composite scaffolds can overcome the limitations of conventional ceramic bone substitutes such as brittleness and difficulty in shaping. However, conventional methods for fabricating polymer/bioceramic composite scaffolds often use organic solvents (e.g., the solvent casting and particulate leaching (SC/PL)
Michiko Sato et al.
Biomaterials, 27(11), 2358-2369 (2005-12-13)
In order to improve orthopedic implant performance, the objective of this in vitro study was to synthesize nanocrystalline hydroxyapatite (HA) powders to coat titanium. HA was synthesized through a wet chemical process. The precipitated powders were either sintered at 1100
Influence of temperature, ripening time and calcination on the morphology and crystallinity of hydroxyapatite nanoparticles.
Pang YX, et al.
J. Eur. Ceram. Soc., 23(10), 1697-1704 (2003)
Deepak Bushan Raina et al.
Acta orthopaedica, 91(2), 126-132 (2019-11-05)
Background and purpose - Targeted delivery of drugs is important to achieve efficient local concentrations and reduce systemic side effects. We hypothesized that locally implanted synthetic hydroxyapatite (HA) particles can act as a recruiting moiety for systemically administered drugs, leading
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