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Merck
CN

676713

Sigma-Aldrich

1,2-二溴-3-氯丙烷

97%

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别名:
DBCP
线性分子式:
CH2BrCHBrCH2Cl
CAS号:
分子量:
236.33
Beilstein:
1732077
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

97%

折射率

n/D 1.5542

bp

60-65 °C/7.5 mmHg

密度

2.081 g/mL at 25 °C

SMILES字符串

ClCC(Br)CBr

InChI

1S/C3H5Br2Cl/c4-1-3(5)2-6/h3H,1-2H2

InChI key

WBEJYOJJBDISQU-UHFFFAOYSA-N

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应用

1,2-Dibromo-3-chloropropane can be used to prepare:
  • Tritium radiolabeled dibromochloropropane.
  • L-Glutathione conjugates, which are used to alkylate the DNA to yield N7-guanyl adducts.

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B - Muta. 1B - Repr. 1A - STOT RE 2 Oral

靶器官

Testes

WGK

WGK 3

闪点(°F)

170.1 °F

闪点(°C)

76.7 °C

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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An improved synthesis of labelled dibromochloropropane
Buchman O, et al.
Journal of Labelled Compounds & Radiopharmaceuticals, 18(12), 1713-1719 (1981)
Isolation and characterization of N7-guanyl adducts derived from 1, 2-dibromo-3-chloropropane
Humphreys WG, et al.
Chemical Research in Toxicology, 4(4), 445-453 (1991)
S Teramoto et al.
Mutation research, 221(1), 1-9 (1989-07-01)
1,2-Dibromo-3-chloropropane (DBCP) is a nematocide, which has been used extensively as a soil fumigant in agriculture. Since sterility was found among male workers involved in the manufacture of DBCP, great concern has been focused on the genetic hazards of DBCP.
1,2-Dibromo-3-chloropropane.
Report on carcinogens : carcinogen profiles, 11, III81-III82 (2004-01-01)
Jinwook Chung et al.
Biodegradation, 18(2), 199-209 (2006-07-06)
We tested the hypothesis that the H(2)-based membrane biofilm reactor (MBfR) is capable of reducing multiple oxidized contaminants, a common situation for groundwater contamination. We conducted bench-scale experiments with three groundwater samples collected from California's San Joaquin Valley and on

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