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Merck
CN

67520

Sigma-Aldrich

1-甲基-L-组氨酸

≥98.0% (TLC), for peptide synthesis

别名:

3-(1-甲基咪唑-4-基)-L-丙氨酸, 3-甲基-L-组氨酸(已废用), Nτ-甲基-L-组氨酸

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About This Item

经验公式(希尔记法):
C7H11N3O2
CAS号:
分子量:
169.18
Beilstein:
9727
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.22

产品名称

1-甲基-L-组氨酸, ≥98.0% (TLC)

质量水平

方案

≥98.0% (TLC)

表单

powder

旋光性

[α]20/D −24±1°, c = 2% in H2O

反应适用性

reaction type: solution phase peptide synthesis

杂质

≤5% water

mp

~240 °C (dec.) (lit.)

应用

peptide synthesis

SMILES字符串

Cn1cnc(C[C@H](N)C(O)=O)c1

InChI

1S/C7H11N3O2/c1-10-3-5(9-4-10)2-6(8)7(11)12/h3-4,6H,2,8H2,1H3,(H,11,12)/t6-/m0/s1

InChI key

BRMWTNUJHUMWMS-LURJTMIESA-N

包装

无底玻璃瓶。内含物装在插入的融合锥内。

其他说明

天然的非蛋白质氨基酸;用作肌蛋白降解指标

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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J Sjölin et al.
Metabolism: clinical and experimental, 36(12), 1175-1184 (1987-12-01)
In order to investigate whether the urinary excretion of 1-methylhistidine (1MH) might serve as an objective indicator of meat ingestion and exogenous 3-methylhistidine (3MH) intake, healthy subjects were fed an ovolactovegetarian diet. At five-day intervals they were given meat of
V.R. Young et al.
The Journal of Biological Chemistry, 247, 293-293 (1972)
J Sjölin et al.
The American journal of clinical nutrition, 50(6), 1407-1414 (1989-12-01)
This investigation was undertaken to determine the splanchnic exchange of 3-methylhistidine (3MH) in infection. Hepatic vein, femoral vein, and radial artery catheterizations were performed in 12 febrile patients with infections of varying severity. Differences in arteriovenous 3MH, analyzed by high-performance
P Betto et al.
Journal of chromatography, 584(2), 256-260 (1992-12-23)
A reversed-phase high-performance liquid chromatographic method is described for the determination of 3-methylhistidine content in human urine using pre-column derivatization with phenylisothiocyanate, isocratic elution with 15 mM sodium acetate-acetonitrile (92:8, v/v) and electrochemical detection. The limit of quantitation was 0.1
K Giesecke et al.
British journal of anaesthesia, 72(6), 697-699 (1994-06-01)
We studied two groups of six patients scheduled for gastrointestinal surgery; they were allocated randomly to receive high- or low-dose fentanyl anaesthesia. The confounding effect of protein balance, before the trauma of surgery, on postoperative nitrogen excretion was controlled by

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