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Merck
CN

67520

1-甲基-L-组氨酸

≥98.0% (TLC), for peptide synthesis

别名:

3-(1-甲基咪唑-4-基)-L-丙氨酸, 3-甲基-L-组氨酸(已废用), Nτ-甲基-L-组氨酸

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关于此项目

经验公式(希尔记法):
C7H11N3O2
化学文摘社编号:
分子量:
169.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
206-368-0
MDL number:
Beilstein/REAXYS Number:
9727
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产品名称

1-甲基-L-组氨酸, ≥98.0% (TLC)

InChI key

BRMWTNUJHUMWMS-LURJTMIESA-N

InChI

1S/C7H11N3O2/c1-10-3-5(9-4-10)2-6(8)7(11)12/h3-4,6H,2,8H2,1H3,(H,11,12)/t6-/m0/s1

SMILES string

Cn1cnc(C[C@H](N)C(O)=O)c1

assay

≥98.0% (TLC)

form

powder

optical activity

[α]20/D −24±1°, c = 2% in H2O

reaction suitability

reaction type: solution phase peptide synthesis

impurities

≤5% water

mp

~240 °C (dec.) (lit.)

application(s)

peptide synthesis

Quality Level

Packaging

无底玻璃瓶。内含物装在插入的融合锥内。

Other Notes

天然的非蛋白质氨基酸;用作肌蛋白降解指标

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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A field study was performed to investigate the acute influence of a milk protein hydrolysate supplemented drink (CHO+PRO) on metabolism during and after a marathon run compared to the same drink without protein (CHO). Carbohydrate metabolites and hormones were not
3-Methylhistidine as a measure of skeletal muscle protein breakdown in human subjects: the case for its continued use.
F J Ballard et al.
Clinical science (London, England : 1979), 65(3), 209-215 (1983-09-01)
J Sjölin et al.
Metabolism: clinical and experimental, 38(1), 23-29 (1989-01-01)
The present investigation was undertaken in order to determine the release of 3-methylhistidine (3MH) from the splanchnic region and from the leg, and the contributions these make to the increase in urinary 3MH excretion in infection. Thirteen febrile patients with
V.R. Young et al.
The Journal of Biological Chemistry, 247, 293-293 (1972)
J Sjölin et al.
Metabolism: clinical and experimental, 36(12), 1175-1184 (1987-12-01)
In order to investigate whether the urinary excretion of 1-methylhistidine (1MH) might serve as an objective indicator of meat ingestion and exogenous 3-methylhistidine (3MH) intake, healthy subjects were fed an ovolactovegetarian diet. At five-day intervals they were given meat of

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