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Merck
CN

674427

Sigma-Aldrich

11-巯基十一烷酸

98%

别名:

MUA, MUDA

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About This Item

线性分子式:
HS(CH2)10CO2H
CAS号:
分子量:
218.36
MDL编号:
UNSPSC代码:
12352103
PubChem化学物质编号:
NACRES:
NA.23

质量水平

方案

98%

表单

solid

mp

46-50 °C (lit.)

储存温度

2-8°C

SMILES字符串

OC(=O)CCCCCCCCCCS

InChI

1S/C11H22O2S/c12-11(13)9-7-5-3-1-2-4-6-8-10-14/h14H,1-10H2,(H,12,13)

InChI key

GWOLZNVIRIHJHB-UHFFFAOYSA-N

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一般描述

11-巯基十一烷酸(MUA)具有长链烷烃链和含羧基的硫醇,它们高度堆积并可形成自组装单层(SAM)。它可以修饰纳米颗粒的表面,以利于将其分散至基于水和溶剂的介质中。

应用

通过通常在生物医学应用中使用的Murray置换反应,MUA可用于1-十二烷硫醇保护的金纳米颗粒(AuNPs)的羧酸官能化。它也可通过创建具有高表面覆盖率的配体纳米组装体,来对铂纳米颗粒(PtNP)的表面进行修饰,从而用于表面增强拉曼光谱(SERS)分析。单细胞生物芯片平台可以利用细胞附着技术进行开发,其中MUA会形成附着至单细胞的SAM。MUA可用于制备四氟苯基活化的酯自组装单层膜,从而对胺修饰的寡核苷酸 和DNA进行固定化。 它还可用于为等离子生物传感器创建3D组装的金纳米结构。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

No data available

闪点(°C)

No data available

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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Thermogravimetry and evolved gas analysis for the investigation of ligand-exchange reaction in thiol-functionalized gold nanoparticles.
Locardi F, et al.
Journal of Analytical and Applied Pyrolysis, 132(5), 11-18 (2018)
Development of single cell biochip platform based on silicon for multiple patch clamping technology.
2009 IEEE 3rd International Conference on Nano/Molecular Medicine and Engineering, 29(6), 138-141 (2009)
Longhua Guo et al.
Analytical chemistry, 82(12), 5147-5153 (2010-05-18)
Three-dimensional gold nanoarchitecture was fabricated by layer-by-layer (LbL) deposition of gold nanoparticles (AuNPs) and multiwalled carbon nanotubes (MWCNTs) on a glass substrate for a highly sensitive plasmonic biosensor using a conventional UV-vis instrument. Carboxyl-functionalized MWCNTs were reacted with 3-mercaptopropyltriethoxysilane (MPTES)
Yonghai Song et al.
Microscopy research and technique, 68(2), 59-64 (2005-10-18)
Immobilized DNA on preformed 11-mercaptoundecanoic acids (MUDA) self-assembled monolayers (SAMs) on a gold (111) surface was bound by a divalent cation bridges was imaged by atomic force microscopy (AFM). The DNA immobilization was attributed to the formation of ionic bridges
Fabrication and characterisation of ligand-functionalised ultrapure monodispersed metal nanoparticle nanoassemblies employing advanced gas deposition technique.
Welearegay TG, et al.
Nanotechnology, 29(6), 065603-065603 (2018)

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