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Merck
CN

672084

Sigma-Aldrich

(S)-(氨甲基)-1-BOC-吡咯烷

97%

别名:

(R)-2-氨甲基-1-叔丁氧羰基吡咯烷, (S)-2-氨甲基吡咯烷-1-甲酸叔丁酯

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About This Item

经验公式(希尔记法):
C10H20N2O2
分子量:
200.28
Beilstein:
8905233
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.22

方案

≥96.5% (GC)
96.5-103.5% (NT)
97%

表单

solid

光学纯度

enantiomeric excess: ≥97.5% (GC)

储存温度

2-8°C

SMILES字符串

CC(C)(C)OC(=O)N1CCC[C@H]1CN

InChI

1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(12)7-11/h8H,4-7,11H2,1-3H3/t8-/m0/s1

InChI key

SOGXYCNKQQJEED-QMMMGPOBSA-N

应用

(S)-2-(Aminomethyl)-1-Boc-pyrrolidine can be used as a building block to synthesize:
  • Imidazo[1,2-b]pyridazine derivatives as potent IKKβ inhibitors.
  • 1,2-dicarba-closo-dodecaborane (o-carborane) and 1,7-dicarba-closo-dodecaborane (m-carborane) derivatives as potential D2 receptor antagonists.
  • Pyrrolidine based Merrifield resin as a chiral organocatalyst for the asymmetric Michael addition reaction of ketones with nitrostyrenes.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Skin Corr. 1B

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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分析证书(COA)

Lot/Batch Number

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访问文档库

Discovery of imidazo [1, 2-b] pyridazines as IKK? inhibitors. Part 3: Exploration of effective compounds in arthritis models
Shimizu H, et al.
Bioorganic & Medicinal Chemistry Letters, 21(15), 4550-4555 (2011)
Synthesis of D2 receptor ligand analogs incorporating one dicarba-closo-dodecaborane unit
Vazquez, N, et al.
Tetrahedron Letters, 52(5), 615-618 (2011)
Recyclable Merrifield resin-supported organocatalysts containing pyrrolidine unit through A3-coupling reaction linkage for asymmetric Michael addition
Liu J, et al.
Chirality, 22(4), 432-441 (2010)

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