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质量水平
方案
95% (HPLC)
反应适用性
reagent type: cross-linking reagent
官能团
Fmoc
amine
carboxylic acid
储存温度
−20°C
SMILES字符串
O=C(CCC(O)=O)NCCCOCCOCCOCCCNC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O
InChI
1S/C19H36N2O8/c1-19(2,3)29-18(25)21-9-5-11-27-13-15-28-14-12-26-10-4-8-20-16(22)6-7-17(23)24/h4-15H2,1-3H3,(H,20,22)(H,21,25)(H,23,24)
InChI key
RTHQDNQOODHVLK-UHFFFAOYSA-N
Journal of visualized experiments : JoVE, (145) (2019-03-26)
Maleimide-bearing bifunctional probes have been employed for decades for the site-selective modification of thiols in biomolecules, especially antibodies. Yet maleimide-based conjugates display limited stability in vivo because the succinimidyl thioether linkage can undergo a retro-Michael reaction. This, of course, can
商品
Polyethylene glycol (PEG) reagents offer favorable characteristics for various applications, including biocompatibility and solubility.
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