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About This Item
线性分子式:
H2NC4H6CO2H
CAS号:
分子量:
115.13
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.22
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质量水平
方案
97%
表单
solid
反应适用性
reaction type: solution phase peptide synthesis
mp
261 °C (dec.) (lit.)
应用
peptide synthesis
SMILES字符串
NC1(CCC1)C(O)=O
InChI
1S/C5H9NO2/c6-5(4(7)8)2-1-3-5/h1-3,6H2,(H,7,8)
InChI key
FVTVMQPGKVHSEY-UHFFFAOYSA-N
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警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
1-Aminocyclobutane-1-carboxylate (ACBC): a specific antagonist of the N-methyl-D-aspartate receptor coupled glycine receptor.
W F Hood et al.
European journal of pharmacology, 161(2-3), 281-282 (1989-02-28)
Insulin-induced phospho-oligosaccharide stimulates amino acid transport in isolated rat hepatocytes.
I Varela et al.
The Biochemical journal, 267(2), 541-544 (1990-04-15)
The ability of the insulin-induced phospho-oligosaccharide to stimulate amino acid transport was studied in isolated rat hepatocytes. At low alpha-aminoisobutyric acid concentrations (0.1 mM), both 100 nM-insulin and 10 microM-phospho-oligosaccharide doubled amino acid uptake after 2 h of incubation. This
Y Gaoni et al.
Journal of medicinal chemistry, 37(25), 4288-4296 (1994-12-09)
A range of cis- and trans-3-substituted 1-aminocyclobutane-1-carboxylic acids has been synthesized and evaluated for antagonism at excitatory amino acid receptor sites and for anticonvulsant activity. Potent and selective antagonist activity at N-methyl-D-aspartate (NMDA) receptor sites in neonatal rat motoneurones was
V N Balaji et al.
Peptide research, 8(3), 178-186 (1995-05-01)
Conformationally constrained peptidomimetics are being increasingly used in the development of 3-D pharmacophores of peptide-based drug candidates and to alter their metabolic stability towards achievements of oral bioavailability. Here we present conformational energy calculations on model compounds containing 1-aminocyclobutane carboxylic
T S Rao et al.
Neuropharmacology, 29(3), 305-309 (1990-03-01)
Following intravenous administration, 1-aminocyclobutane-1-carboxylate (ACBC, 100 mg/kg), a N-methyl-D-aspartate (NMDA)-associated glycine receptor antagonist, was eliminated with a T1/2 of 5 min in mouse brain and 4 min in rat cerebrospinal fluid (CSF). 1-Aminocyclopropane-1-carboxylate (ACC), a NMDA-associated glycine receptor agonist, was
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