所有图片(1)
About This Item
经验公式(希尔记法):
13C3C8H19NO9
CAS号:
分子量:
312.25
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.12
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同位素纯度
≥99 atom % 13C
质量水平
方案
≥97% (CP)
mp
186 °C (lit.)
质量偏移
M+3
储存温度
−20°C
SMILES字符串
CC(=O)N[C@@H]1[C@@H](O)[13CH2][13C](O)(O[C@H]1[C@H](O)[C@H](O)CO)[13C](O)=O
InChI
1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11?/m0/s1/i2+1,10+1,11+1
InChI key
SQVRNKJHWKZAKO-JQVNYIDJSA-N
一般描述
N-乙酰基-D-神经氨酸-1,2,3-13C3 是N-乙酰基-D-神经氨酸的同位素。
应用
N-乙酰基-D-神经氨酸-1,2,3-13C3 可用于通过13C NMR波谱仪定量测定无环酮、酮水合物和烯醇。它也可用于测定作为NANS缺陷患者治疗途径的唾液酸增补剂。
包装
该产品可以大包装形式供货,也可按需进行包装。 如需关于价格、供货形式及包装的信息,请联系稳定同位素客户服务。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Lilian Dubois et al.
Journal of medicinal chemistry, 63(15), 8231-8249 (2020-07-02)
Sialin, encoded by the SLC17A5 gene, is a lysosomal sialic acid transporter defective in Salla disease, a rare inherited leukodystrophy. It also enables metabolic incorporation of exogenous sialic acids, leading to autoantibodies against N-glycolylneuraminic acid in humans. Here, we identified
Mark D Jankowski et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 238, 110336-110336 (2019-09-03)
Understanding variation in physiological traits across taxa is a central question in evolutionary biology that has wide-ranging implications in biomedicine, disease ecology, and environmental protection. Sialic acid (Sia), and in particular, 5-N-acetylneuraminic acid (Neu5Ac), is chemically bound to galactose and
Christel Tran et al.
Molecular genetics and metabolism reports, 28, 100777-100777 (2021-07-15)
In NANS deficiency, biallelic mutations in the N-acetylneuraminic acid synthase (NANS) gene impair the endogenous synthesis of sialic acid (N-acetylneuraminic acid) leading to accumulation of the precursor, N-acetyl mannosamine (ManNAc), and to a multisystemic disorder with intellectual disability. The aim
Thomas Klepach et al.
Journal of the American Chemical Society, 130(36), 11892-11900 (2008-08-20)
Aqueous solutions of N-acetyl-neuraminic acid (Neu5Ac, 1) labeled with (13)C at C1, C2, and/or C3 were analyzed by (13)C NMR spectroscopy to detect and quantify the acyclic forms (keto, keto hydrate, enol) present at varying pHs. In addition to pyranoses
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