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线性分子式:
CH3SO2NH2
化学文摘社编号:
分子量:
95.12
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
221-553-6
Beilstein/REAXYS Number:
1740835
MDL number:
Assay:
≥97.0% (CHN)
Form:
solid
InChI key
HNQIVZYLYMDVSB-UHFFFAOYSA-N
InChI
1S/CH5NO2S/c1-5(2,3)4/h1H3,(H2,2,3,4)
SMILES string
CS(N)(=O)=O
assay
≥97.0% (CHN)
form
solid
mp
85-89 °C (lit.)
Quality Level
Application
- 甲磺酰胺用于合成重要的有机试剂,如 N -(2-甲硫基-1- p -甲苯磺酰)甲磺酰胺和 叔 -丁基((2-(三甲基硅基)乙基)磺酰基)氨基甲酸酯。
- 可作为氮源用于羧酸转化为相应的的腈。
- 它作为一种试剂被广泛用于合成药物上重要的化合物,如吲哚衍生物 N -乙酰胺 、甲磺酰胺嘧啶取代的 3,5-二羟基-6-庚烯酸类 和 repertaxin 。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Development and preliminary optimization of indole-N-acetamide inhibitors of hepatitis C virus NS5B polymerase.
Harper S, et al.
Journal of Medicinal Chemistry, 48(5), 1314-1317 (2005)
Methanesulfonamide.
eEROS (Encyclopedia of Reagents for Organic Synthesis) (2007)
Sunil Kumar Singh et al.
Bioorganic & medicinal chemistry letters, 14(7), 1683-1688 (2004-03-18)
The effect of methanesulfonamide (MeSO(2)NH) group on COX-2 inhibitory activity of 1,5-diarylpyrazole is described. While this group being at position-4 of the N(1)-phenyl ring was found to be ineffective, its installation at position-4 of the C-5 phenyl ring offered several
Sevgi Karakuş et al.
European journal of medicinal chemistry, 44(9), 3591-3595 (2009-03-28)
Due to a continuing effort to develop new antiviral agents, a series of 1-[4-(methanesulfonamido)-3-phenoxyphenyl]-3-alkyl/aryl thioureas 3a-i have been synthesized by the reaction of alkyl/aryl isothiocyanates with 4-amino-2-phenoxymethanesulfonanilide. These derivatives were structurally characterized by the use of spectral techniques and evaluated
A Convenient Synthesis of Chloronitrobenzonitrile Isomers and Homologs.
Grivsky E M
Bull. Soc. Chim. Belg., 80(3?4), 245-252 (1971)
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