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Merck
CN

637750

Sigma-Aldrich

5-溴-2-碘嘧啶

97%

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About This Item

经验公式(希尔记法):
C4H2BrIN2
分子量:
284.88
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

97%

形式

solid

mp

99-103 °C (lit.)

SMILES字符串

Brc1cnc(I)nc1

InChI

1S/C4H2BrIN2/c5-3-1-7-4(6)8-2-3/h1-2H

InChI key

ZEZKXPQIDURFKA-UHFFFAOYSA-N

一般描述

5-Bromo-2-iodopyrimidine can be synthesized by reacting 5-bromo-2-chloropyrimidine with hydroiodic acid.

应用

5-Bromo-2-iodopyrimidine can be used to synthesize 5,5′-dibromo-2,2′-bipyrimidine and O,O′-dimethyl hyrtinadine A.

象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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"One-Pot Synthesis of Diazine-Bridged Bisindoles and Concise Synthesis of the Marine Alkaloid Hyrtinadine A"
Tasch.O.A.B, et al.
European Journal of Organic Chemistry, 2011(24), 4532- 4535 (2011)
Gábor Vlád et al.
The Journal of organic chemistry, 67(18), 6550-6552 (2002-08-31)
A high-yield synthesis was developed for the preparation of 2,2'-bipyrimidine (1) using the Ullmann coupling of 2-iodopyrimidine. The new procedure was also used for the preparation of 4,4',6,6'-tetramethyl-2,2'-bipyrimidine (2) and 5,5'-dibromo-2,2'-bipyrimidine (3).

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