579602
(R)-(+)-1,2-二硫戊环基-3-戊酸
97%
别名:
(R)-6,8-二硫辛酸, (R)-6,8-硫辛酸
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关于此项目
经验公式（希尔记法）:
C8H14O2S2
化学文摘社编号:
分子量:
206.33
UNSPSC Code:
12352005
PubChem Substance ID:
MDL number:
Assay:
97%
Form:
solid
form
solid
InChI
1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1
InChI key
AGBQKNBQESQNJD-SSDOTTSWSA-N
assay
97%
optical activity
[α]20/D +104°, c = 1 in chloroform
mp
48-52 °C (lit.)
存储类别
11 - Combustible Solids
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Alessandra Antonello et al.
Journal of medicinal chemistry, 48(1), 28-31 (2005-01-07)
To combine in the same molecule alpha(1)-adrenoreceptor blocking and antioxidant properties, compounds 2-5 were designed and synthesized. All compounds were effective alpha(1)-adrenoreceptor antagonists and were tested in both functional and binding assays. In addition, compounds 2 and 5 also displayed
Michela Rosini et al.
Journal of medicinal chemistry, 48(2), 360-363 (2005-01-22)
The coupling of two different pharmacophores, each endowed with different biological properties, afforded the hybrid compound lipocrine (7), whose biological profile was markedly improved relative to those of prototypes tacrine and lipoic acid. Lipocrine is the first compound that inhibits
A S Loginov et al.
Farmakologiia i toksikologiia, 52(4), 78-82 (1989-07-01)
The features of the pharmacokinetics of preparations of alpha-lipoic acid (lipoic acid, thioctacide) as compared with their pharmacodynamic effects were studied in 125 patients with chronic diffuse diseases of the liver of viral and alcohol etiology. After a single administration
D B McCormick
The Journal of nutrition, 130(2S Suppl), 323S-330S (2000-03-18)
Over the span of 40 y and with the participation of over 60 students and postdoctoral colleagues, my laboratory has been able to elucidate numerous aspects of cofactor metabolism and function. Findings have been on the absorption, transport, utilization and
P R Redden et al.
International journal of pharmaceutics, 180(2), 151-160 (1999-06-17)
A series of acyloxymethyl drug derivatives of the NH-acidic drugs, phenytoin and theophylline and of the carboxylic acid drugs, thioctic acid and indomethacin, were prepared in order to determine the effect of varying the nature of the drug on the
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