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Merck
CN

574759

Sigma-Aldrich

顺-四氯二氨铂(IV)

99.9% trace metals basis

别名:

cis -Diamminetetrachloroplatinum, cis-Tetrachlorodiammineplatinum

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About This Item

线性分子式:
Pt(NH3)2Cl4
CAS号:
分子量:
370.95
EC 号:
MDL编号:
UNSPSC代码:
12352302
PubChem化学物质编号:
NACRES:
NA.23
方案:
99.9% trace metals basis
表单:
powder

方案

99.9% trace metals basis

表单

powder

mp

>300 °C (lit.)

SMILES字符串

N.N.Cl[Pt](Cl)(Cl)Cl

InChI

1S/4ClH.2H3N.Pt/h4*1H;2*1H3;/q;;;;;;+4/p-4

InChI key

RBHOYUZKIANPPG-UHFFFAOYSA-J

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警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Sens. 1

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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H Razaka et al.
Chemico-biological interactions, 60(2), 207-215 (1986-11-01)
After exposure of bacteria to equal concentrations of cis-diamminedichloroplatinum(II) (DDP) and cis-diamminetetrachloroplatinum(IV) (DTP), the intracellular concentration of DTP was an order of magnitude greater than DDP. However, at identical intracellular drug concentrations, the Pt(IV) compound formed only half as many
A C Plooy et al.
Cancer research, 44(5), 2043-2051 (1984-05-01)
Several effects of four diamminechloroplatinum compounds (II and IV) in Chinese hamster ovary cells were studied. The two cis-compounds [cis-diamminedichloroplatinum(II) and cis-diamminetetrachloroplatinum(IV)] are known to possess antitumor activity, whereas the two trans-stereoisomers [trans-diamminedichloroplatinum(II) and trans-diamminetetrachloroplatinum(IV)] are inactive. When the effects
M Defais et al.
Chemico-biological interactions, 74(3), 343-352 (1990-01-01)
DNA strand breaks were observed in bacteria treated with Pt(IV) but not Pt(II) antitumor compounds by two methods. First, compounds which cause DNA strand breaks produced an SOS induction signal which was detected by a rapid bacterial assay. In addition

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