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Merck
CN

567280

Sigma-Aldrich

4-(3-羟丙基)吗啉

95%

别名:

3-(4-吗啉)-1-丙醇, 3-吗啉代-1-丙醇

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About This Item

经验公式(希尔记法):
C7H15NO2
CAS号:
分子量:
145.20
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:

方案

95%

杂质

may contain ~5% morpholine

折射率

n20/D 1.4770 (lit.)

沸点

240-241 °C (lit.)

密度

1.049 g/mL at 25 °C (lit.)

SMILES字符串

OCCCN1CCOCC1

InChI

1S/C7H15NO2/c9-5-1-2-8-3-6-10-7-4-8/h9H,1-7H2

InChI key

VZKSLWJLGAGPIU-UHFFFAOYSA-N

应用

4-(3-Hydroxypropyl)morpholine may be used in the synthesis of macrocyclic urea compounds, which can act as potent Chk1 inhibitors.

象形图

Health hazardCorrosion

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Repr. 2 - Skin Corr. 1B

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 3

闪点(°F)

185.0 °F - closed cup

闪点(°C)

85 °C - closed cup

法规信息

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分析证书(COA)

Lot/Batch Number

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访问文档库

"Synthesis and in-vitro biological activity of macrocyclic urea Chk1 inhibitors"
Li J, et al.
Bioorganic & Medicinal Chemistry Letters, 17(23), 6499-6504 (2007)
David Johansson et al.
BMC cancer, 9, 67-67 (2009-02-28)
The prerequisite for the potential use of the bacterial toxin verotoxin-1 in the treatment of breast cancer was investigated by first determining the expression of its receptor Gb3 (CD77) in clinical breast cancer tissue specimens. We then examined the cytotoxicity
Y Jiang et al.
Journal of biological regulators and homeostatic agents, 34(6), 2029-2036 (2020-12-12)
Dysregulation of the adipo-osteogenic differentiation balance of mesenchymal stem cells (MSCs), which are common progenitor cells of adipocytes and osteoblasts, has been associated with many pathophysiologic diseases, such as obesity, osteopenia, and several neurodegenerative disorders. Growing evidence suggests that lipid
Weihong Xu et al.
Biochemical and biophysical research communications, 463(4), 545-550 (2015-06-01)
In the current study, we investigated the potential activity of AR-42, a novel histone deacetylase (HDAC) inhibitor, against colon cancer cells. Our in vitro results showed that AR-42 induced ceramide production, exerted potent anti-proliferative and pro-apoptotic activities in established (SW-620 and

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