推荐产品
旋光性
[α]20/D +19°, neat
折射率
n20/D 1.551 (lit.)
沸点
67-68 °C/1 mmHg (lit.)
密度
1.214 g/mL at 25 °C (lit.)
官能团
chloro
ether
SMILES字符串
Clc1cccc(c1)[C@@H]2CO2
InChI
1S/C8H7ClO/c9-7-3-1-2-6(4-7)8-5-10-8/h1-4,8H,5H2/t8-/m0/s1
InChI key
YVMKRPGFBQGEBF-QMMMGPOBSA-N
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应用
(R)-(+)-3-Chlorostyrene oxide may be used as an intermediate for the synthesis of 4-aminopiperidine based human β3-adrenergic receptor (AR) agonists.
Reactant involved in:
- Diastereoselective Wadsworth-Emmons cyclopropanation for synthesis of quaternaty cyclopropyl esters
- Synthesis of phenylethanolamine derivatives as β3-adrenergic receptor agonists
- Stereoselective ring-opening for synthesis of β-aryloxy-substituted alcohols and amines
- Synthesis of Biphenyl benzoic acid derivatives as β3-adrenergic receptor agonists
- Synthesis of (S)-2-, 3-, and 4-chlorostyrene oxides with epoxide hydrolase
警示用语:
Warning
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官
Respiratory system
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
206.6 °F - closed cup
闪点(°C)
97 °C - closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
4-Aminopiperidine ureas as potent selective agonists of the human ? 3-Adrenergic receptor.
Bioorganic & Medicinal Chemistry Letters, 11(24), 3123-3127 (2001)
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