56160
L-(+)-对羟基苯甘氨酸
≥99.0% (NT)
别名:
(2S)-2-Amino-2-(4-hydroxyphenyl)acetic acid, Oxfenicine
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关于此项目
经验公式（希尔记法）:
C8H9NO3
化学文摘社编号:
分子量:
167.16
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
251-061-7
MDL number:
Beilstein/REAXYS Number:
3589845
InChI key
LJCWONGJFPCTTL-ZETCQYMHSA-N
InChI
1S/C8H9NO3/c9-7(8(11)12)5-1-3-6(10)4-2-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m0/s1
SMILES string
N[C@H](C(O)=O)c1ccc(O)cc1
assay
≥99.0% (NT)
form
solid
optical activity
[α]20/D +158±3°, c = 1% in 1 M HCl
reaction suitability
reaction type: solution phase peptide synthesis
application(s)
peptide synthesis
Quality Level
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Wendy Keung et al.
Diabetes, 62(3), 711-720 (2012-11-10)
Impaired skeletal muscle fatty acid oxidation has been suggested to contribute to insulin resistance and glucose intolerance. However, increasing muscle fatty acid oxidation may cause a reciprocal decrease in glucose oxidation, which might impair insulin sensitivity and glucose tolerance. We
Khalid Abozguia et al.
Nature clinical practice. Cardiovascular medicine, 3(9), 490-498 (2006-08-26)
Despite advances in treatment, chronic heart failure is still associated with significant morbidity and a poor prognosis. The scope for further advances based on additional neurohumoral blockade is small. Effective adjunctive therapies acting via a different cellular mechanism would, therefore
Xihou Yin et al.
Microbiology (Reading, England), 152(Pt 10), 2969-2983 (2006-09-29)
The biosynthetic gene cluster for the 17 aa peptide antibiotic enduracidin has been cloned and sequenced from Streptomyces fungicidicus ATCC 21013. The 84 kb gene cluster contains 25 ORFs and is located within a 116 kb genetic locus that was
Chung-Jen Chiang et al.
Journal of agricultural and food chemistry, 56(15), 6348-6354 (2008-07-19)
Optically pure amino acids have been widely used as intermediates in the synthesis of antibiotics, antifungal agents, pesticides, and sweeteners. Of particular importance, d- p-hydroxyphenylglycine (D-HPG) can be produced from d, l-hydroxyphenly hydantoin (D,L-HPH) in a two-step reaction mediated by
Jeanne M Davidsen et al.
Journal of bacteriology, 191(3), 1066-1077 (2008-11-26)
Nocardicin A is a monocyclic beta-lactam isolated from the actinomycete Nocardia uniformis, which shows moderate activity against a broad spectrum of gram-negative bacteria. Within the biosynthetic gene cluster of nocardicin A, nocR encodes a 583-amino-acid protein with high similarity to
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