质量水平
检测方案
97%
形式
solid
mp
154-158 °C (lit.)
SMILES字符串
Oc1nsc2ccccc12
InChI
1S/C7H5NOS/c9-7-5-3-1-2-4-6(5)10-8-7/h1-4H,(H,8,9)
InChI key
DMSMPAJRVJJAGA-UHFFFAOYSA-N
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一般描述
1,2-苯并异噻唑3（2H）-酮可以通过使2-巯基苯甲酸与二苯基磷酰基叠氮化物反应来合成。
免责声明
本品不可用作全球生物杀灭剂法规监管的生物杀灭剂，包括但不限于：美国联邦杀虫剂、杀菌剂和灭鼠剂法(US EPA′s Federal Insecticide Fungicide and Rodenticide Act)、欧盟生物杀灭剂法规(European Biocidal Products Regulation)、加拿大虫害管理监管机构(Canada’s Pest Management Regulatory Agency)、土耳其生物杀灭剂法规(Turkey’s Biocidal Products Regulation)、韩国生物杀灭剂法(Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR))等。
警示用语：
Danger
危险分类
Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
农药列管产品
Convenient Synthesis of 1, 2-Benzisothiazol-3 (2H)-ones by Cyclization Reaction
of Acyl Azide
of Acyl Azide
Chiyoda T, et al.
Synlett, 2000(10), 1427-1428 (2000)
Kristiina Aalto-Korte et al.
Archives of dermatology, 142(10), 1326-1330 (2006-10-18)
Contact allergy to plastic gloves is rare. Benzisothiazolinone is a biocide that is mainly used in industrial settings. We first suspected delayed-type contact allergy to benzisothiazolinone from polyvinyl chloride (PVC) gloves in 2004. We looked through our medical records from
Mahalakshmi Vasan et al.
ChemMedChem, 5(12), 2079-2087 (2010-11-06)
A simple steady-state kinetic high-throughput assay was developed for the salicylate synthase MbtI from Mycobacterium tuberculosis, which catalyzes the first committed step of mycobactin biosynthesis. The mycobactins are small-molecule iron chelators produced by M. tuberculosis, and their biosynthesis has been identified
Dengfeng Dou et al.
Bioorganic & medicinal chemistry, 19(19), 5782-5787 (2011-09-10)
A series of broad-spectrum antifungal agents based on the 1,2-benzisothiazol-3(2H)-one scaffold is reported. Preliminary structure-activity relationship studies have established the importance of the presence of the heterocyclic ring, a methyl group, and a phenyl ring for optimal manifestation of antifungal
G Moscato et al.
Occupational medicine (Oxford, England), 47(4), 249-251 (1997-05-01)
We report a case of occupational asthma and rhinitis caused by inhalation of 1,2-benzisothiazolin-3-one, an additive used as a microbicidal in detergent production, in a 26-year-old man employed in a chemical factory producing detergents. The subject's task consisted of pouring
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