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检测方案
97%
形式
solid
mp
78-82 °C (lit.)
SMILES字符串
CC(C)(C)OC(=O)N1CCC(CO)CC1
InChI
1S/C11H21NO3/c1-11(2,3)15-10(14)12-6-4-9(8-13)5-7-12/h9,13H,4-8H2,1-3H3
InChI key
CTEDVGRUGMPBHE-UHFFFAOYSA-N
一般描述
N-Boc-4-哌啶甲醇含有一个叔丁氧羰基(t-BOC)-保护基团。可由4-哌啶甲醇与焦碳酸二叔丁酯反应合成。
应用
N-Boc-4-哌啶甲醇可用于合成：
- 5-甲氧基-4-(1-甲基哌啶-4-基甲氧基)-2-硝基苯甲酸甲酯
- N-Boc-4-哌啶醛
- [1-(叔丁氧羰基)哌啶-4-基]甲磺酸甲酯
参与减慢心率药合成。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
Synthesis and nanostructures of 5, 10, 15, 20-tetrakis (4-piperidyl) porphyrin.
JacobsenJL, et al.
Tetrahedron, 69(48), 10507-10515 (2013)
Hideki Kubota et al.
Bioorganic & medicinal chemistry letters, 14(12), 3049-3052 (2004-05-20)
A series of piperidinoalkanoyl-1,2,3,4-tetrahydroisoquinoline derivatives were synthesized, and their bradycardic activities were investigated in the isolated right atria of guinea pigs and in conscious rats. These efforts identified the achiral compound 2f, which exhibited potent and long-lasting bradycardic activity with
Daniele Zampieri et al.
European journal of medicinal chemistry, 44(1), 124-130 (2008-04-29)
We describe here the synthesis and the binding interaction with sigma(1) and sigma(2) receptors of a series of new benzo[d]oxazol-2(3H)-one derivatives variously substituted on the N-benzyl moiety. The results of binding studies confirm the notion that the benzoxazolone moiety confers
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