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Merck
CN

555797

Sigma-Aldrich

3-氨基-2-甲基-4(3H)-喹唑啉酮

98%

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经验公式(希尔记法):
C9H9N3O
CAS号:
分子量:
175.19
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:

检测方案

98%

形式

solid

mp

149-152 °C (lit.)

SMILES字符串

CC1=Nc2ccccc2C(=O)N1N

InChI

1S/C9H9N3O/c1-6-11-8-5-3-2-4-7(8)9(13)12(6)10/h2-5H,10H2,1H3

InChI key

IQOUPYQSZBDNAW-UHFFFAOYSA-N

一般描述

3-Amino-2-methyl-4(3H)quinazolinone is a quinazoline derivative. 2-Methyl-3,1-benzoxazin-4-one undergoes condensation reaction with hydrazine hydrate to yield 3-amino-2-methyl-4(3H)quinazolinone. It undergoes condensation with various substituted aldehydes to afford Schiff′s bases.

应用

3-Amino-2-methyl-4(3H)quinazolinone may be used to synthesize:
  • 2-methyl-3-[3′-aminophthalimido]-4(3H)-quinazolinone
  • 2-alkyl-3-(methylamino)-4(3H)-quinazolinone
  • 3-amino-2-chloromethyl-4(3H)-quinazolinone

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Disperse dyes based on 2-methyl-3-[3'-amino-phthalimido]-4 (3H)-quinazilinone.
Patel VH, et al.
J. Serb. Chem. Soc., 67(11), 719-726 (2002)
Dipolar Cycloaddition Reactions with Quinazolinones: A New Route for the Synthesis of Several Annelated Pyrrolo-and Pyridazinoquinazoline Derivatives.
Ghabrial SS and Gaber HM.
Molecules (Basel), 8(5), 401-410 (2003)
Kollur Shiva Prasad et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 81(1), 276-282 (2011-07-12)
Four Schiff base ligands and their corresponding organotin(IV) complexes have been synthesized and characterized by elemental analyses, IR, (1)H NMR, MS and thermal studies. The Schiff bases are obtained by the condensation of 3-amino-2-methyl-4(3H)-quinazolinone with different substituted aldehydes. The elemental

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