所有图片(1)
About This Item
线性分子式:
(C6H5CH2COS)2
CAS号:
分子量:
302.41
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
推荐产品
质量水平
方案
96%
表单
solid
mp
59-63 °C (lit.)
官能团
disulfide
phenyl
SMILES字符串
O=C(Cc1ccccc1)SSC(=O)Cc2ccccc2
InChI
1S/C16H14O2S2/c17-15(11-13-7-3-1-4-8-13)19-20-16(18)12-14-9-5-2-6-10-14/h1-10H,11-12H2
InChI key
IXGZXXBJSZISOO-UHFFFAOYSA-N
一般描述
苯乙酰二硫化物在磷酸盐制备过程中用作硫化试剂。苯乙硫醇磺酸盐与硫代乙酸在三乙胺的作用下反应可合成苯基乙酰二硫化物。
应用
苯乙酰二硫化物（PADS）可作为硫转移剂用于硫代磷酸寡核苷酸。
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Honglu Zhang et al.
Journal of the American Chemical Society, 128(51), 16464-16465 (2006-12-21)
The activation of phosphatidylinositol 3-kinase (PI 3-K) and subsequent production of PtdIns(3,4,5)P3 launches a signal transduction cascade that impinges on a plethora of downstream effects on cell physiology. Control of PI 3-K and PtdIns(3,4,5)P3 levels is an important therapeutic target
Use of phenylacetyl disulfide (PADS) in the synthesis of oligodeoxyribonucleotide phosphorothioates.
Cheruvallath ZS, et al.
Nucleosides, nucleotides & nucleic acids, 18(3), 485-492 (1999)
Caged O-phosphorothioyl amino acids as building blocks for Fmoc-based solid phase peptide synthesis.
Andreas Aemissegger et al.
Tetrahedron, 63(27), 6185-6190 (2007-07-02)
The synthesis of 1-(2-nitrophenylethyl) caged O-phosphorothioylserine, -threonine and -tyrosine derivatives is reported. These amino acid building blocks can be directly incorporated into peptides by Fmoc-based solid phase synthesis as their pentafluorophenyl esters or as symmetric anhydrides. Upon irradiation with UV
Synthesis of antisense oligonucleotides: Replacement of 3H-1, 2-benzodithiol-3-one 1, 1-dioxide (Beaucage reagent) with phenylacetyl disulfide (PADS) as efficient sulfurization reagent: From bench to bulk manufacture of active pharmaceutical ingredient.
Cheruvallath ZS, et al.
Organic Process Research & Development, 4(3), 199-204 (2000)
A study on the use of phenylacetyl disulfide in the solid-phase synthesis of oligodeoxynucleoside phosphorothioates.
Roelen HCPF, et al.
J. R. Neth. Chem. Soc., 110(7-8), 325-331 (1991)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门