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质量水平
检测方案
97%
mp
175-178 °C (lit.)
SMILES字符串
COc1cc2nc(Cl)nc(Cl)c2cc1OC
InChI
1S/C10H8Cl2N2O2/c1-15-7-3-5-6(4-8(7)16-2)13-10(12)14-9(5)11/h3-4H,1-2H3
InChI key
DGHKCBSVAZXEPP-UHFFFAOYSA-N
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应用
2,4-Dichloro-6,7-dimethoxyquinazoline may be used as a reactant in the preparation of the following potential bioactive compounds:
- 2-chloro-4,6,7-trimethoxyquinazoline
- 2-chloro-6,7-dimethoxy-4(3H)-quinazolinone
- 2,4-diamino-6,7-dimethoxy quinazolines
- 2-chloro-4-(3-bromoanilino)-6,7-dimethoxyquinazoline
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Antihypertensive 2-amino-4 (3H)-quinazolinones.
Hess HJ, et al.
Journal of Medicinal Chemistry, 11(1), 130-136 (1968)
A short and unequivocal synthesis of 5-aminotetrazolo[1,5-a]-quinazoline as a tricyclic analogue of 4-(3-bromoanilino)-6,7-dimethoxyquinazoline (PD 153035).
Bencteux E and Houssin R.
Journal of Heterocyclic Chemistry, 34(4), 1375-1378 (1997)
Discovery of a 2, 4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a.
Liu F, et al.
Journal of Medicinal Chemistry, 52(24), 7950-7953 (2009)
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