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Merck
CN

550019

Sigma-Aldrich

N,N-二甲基亚二丙基三胺

99%

别名:

DMAPAPA

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About This Item

线性分子式:
(CH3)2N(CH2)3NH(CH2)3NH
CAS号:
分子量:
159.27
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

99%

折射率

n20/D 1.4630 (lit.)

沸点

220 °C (lit.)

密度

0.883 g/mL at 25 °C (lit.)

官能团

amine

SMILES字符串

CN(C)CCCNCCCN

InChI

1S/C8H21N3/c1-11(2)8-4-7-10-6-3-5-9/h10H,3-9H2,1-2H3

InChI key

OMKZWUPRGQMQJC-UHFFFAOYSA-N

一般描述

N,N-二甲基二丙烯三胺是一种脂肪族无环胺,通常用于开发基因传递的聚合体系。

应用

N,N-二甲基二丙烯三胺(DP)可用于:
  • 制备可生物降解的两亲性聚阳离子共聚物聚环氧乙烷-b-聚(3-己内酯-g-DP)[PEO-b-P(CL-g-DP)]。
  • 开发第二代氨基糖苷 6′-N-乙酰基转移酶(AAC(6′)抑制剂。
  • 制备可用于治疗胰腺癌的亲水性吉西他滨共轭阳离子共聚物。

法律信息

Arkema Inc. 产品

警示用语:

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Corr. 1A - Skin Sens. 1

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 1

闪点(°F)

210.2 °F - closed cup

闪点(°C)

99 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Xiao-Bing Xiong et al.
Biomaterials, 30(2), 242-253 (2008-10-08)
The RNA interference (RNAi) technology has been successfully used in elucidating mechanisms behind various biological events. However, in the absence of safe and effective carriers for in vivo delivery of small interfering RNAs (siRNAs), application of this technology for therapeutic
Feng Gao et al.
Journal of medicinal chemistry, 49(17), 5273-5281 (2006-08-18)
Truncated aminoglycoside-coenzyme A bisubstrate analogues were efficiently prepared using a convergent approach where the amine and the thiol are coupled in one pot with the addition of a linker, without the need for protecting groups. These derivatives were tested for
Anupama Mittal et al.
Biomaterials, 35(25), 7077-7087 (2014-05-20)
Clinical effectiveness of gemcitabine in pancreatic cancer is hindered due to its rapid plasma metabolism and development of chemo-resistance. We have previously delineated the significant role of miRNAs in mediating the growth and proliferation of cancer stem cells (CSCs) which
[Toxicity of several aliphatic amines].
G I Sidorin et al.
Gigiena truda i professional'nye zabolevaniia, (11)(11), 50-53 (1984-11-01)
J Shen et al.
Biomaterials, 34(18), 4520-4531 (2013-03-23)
The low toxicity and efficient gene delivery of polymeric vectors remain the major barrier to the clinical application of non-viral gene therapy. Here, we present a poly-D, L-succinimide (PSI)-based biodegradable cationic polymer which mimicked the golden standard, branched polyethylenimine (PEI

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