所有图片(3)
About This Item
线性分子式:
(CH3)2N(CH2)3NH(CH2)3NH
CAS号:
分子量:
159.27
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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质量水平
方案
99%
折射率
n20/D 1.4630 (lit.)
沸点
220 °C (lit.)
密度
0.883 g/mL at 25 °C (lit.)
官能团
amine
SMILES字符串
CN(C)CCCNCCCN
InChI
1S/C8H21N3/c1-11(2)8-4-7-10-6-3-5-9/h10H,3-9H2,1-2H3
InChI key
OMKZWUPRGQMQJC-UHFFFAOYSA-N
一般描述
N,N-二甲基二丙烯三胺是一种脂肪族无环胺,通常用于开发基因传递的聚合体系。
应用
N,N-二甲基二丙烯三胺(DP)可用于:
- 制备可生物降解的两亲性聚阳离子共聚物聚环氧乙烷-b-聚(3-己内酯-g-DP)[PEO-b-P(CL-g-DP)]。
- 开发第二代氨基糖苷 6′-N-乙酰基转移酶(AAC(6′)抑制剂。
- 制备可用于治疗胰腺癌的亲水性吉西他滨共轭阳离子共聚物。
法律信息
Arkema Inc. 产品
警示用语:
Danger
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Corr. 1A - Skin Sens. 1
储存分类代码
8A - Combustible corrosive hazardous materials
WGK
WGK 1
闪点(°F)
210.2 °F - closed cup
闪点(°C)
99 °C - closed cup
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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Truncated aminoglycoside-coenzyme A bisubstrate analogues were efficiently prepared using a convergent approach where the amine and the thiol are coupled in one pot with the addition of a linker, without the need for protecting groups. These derivatives were tested for
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Biomaterials, 35(25), 7077-7087 (2014-05-20)
Clinical effectiveness of gemcitabine in pancreatic cancer is hindered due to its rapid plasma metabolism and development of chemo-resistance. We have previously delineated the significant role of miRNAs in mediating the growth and proliferation of cancer stem cells (CSCs) which
[Toxicity of several aliphatic amines].
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Gigiena truda i professional'nye zabolevaniia, (11)(11), 50-53 (1984-11-01)
J Shen et al.
Biomaterials, 34(18), 4520-4531 (2013-03-23)
The low toxicity and efficient gene delivery of polymeric vectors remain the major barrier to the clinical application of non-viral gene therapy. Here, we present a poly-D, L-succinimide (PSI)-based biodegradable cationic polymer which mimicked the golden standard, branched polyethylenimine (PEI
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