推荐产品
方案
95%
折射率
n20/D 1.462 (lit.)
密度
1.107 g/mL at 25 °C (lit.)
SMILES字符串
CCOC(=O)CCCCC(Cl)CCCl
InChI
1S/C10H18Cl2O2/c1-2-14-10(13)6-4-3-5-9(12)7-8-11/h9H,2-8H2,1H3
InChI key
RFYDWSNYTVVKBR-UHFFFAOYSA-N
应用
6,8-二氯辛酸乙酯可用作合成6-硒代硫辛酸和α-硫辛酸衍生物的原料，而这些衍生物表现出了有效的抗癌活性。
其还可用作合成以下成分的起始材料：
其还可用作合成以下成分的起始材料：
- 6,8-二苄基巯基辛酸，一种用于制备 DL-α-硫辛酸的中间体。
- 5,7-二氯庚酸乙酯，一种用于制备 DL-1,2-二硫杂环戊酸酯-3-丁酸的中间体。
- 7-溴-1,3-二氯庚烷，一种制备 DL-12-二硫杂环戊酸酯-3-丁烷磺酰胺的中间体。
警示用语：
Warning
危险声明
危险分类
Aquatic Chronic 2 - Skin Sens. 1
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
230.0 °F - closed cup
闪点(°C)
110 °C - closed cup
个人防护装备
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
新产品
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Synthesis of DL-1, 2-Dithiolane-3-caproic Acid and DL-1, 2-Dithiolane-3-butyric Acid, Homologs of a-Lipoic Acid.
Thomas RC and Reed LJ.
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Syntheses of DL-a-lipoic acid.
Reed LJ and Niu CI.
Journal of the American Chemical Society, 77(2), 416-419 (1955)
Synthesis of DL-1, 2-Dithiolane-3-butanesulfonamide, an Analog of a-Lipoic Acid.
Thomas RC and Reed LJ.
Journal of the American Chemical Society, 78(23), 6150-6151 (1956)
Shi-Jie Zhang et al.
Bioorganic & medicinal chemistry letters, 20(10), 3078-3083 (2010-04-21)
alpha-Lipoic acid derivatives were synthesized and evaluated for their in vitro anticancer activities against NCI-460, HO-8910, KB, BEL-7402, and PC-3 cell lines. The results, for most compounds exhibited dose-dependent inhibitory property and several compounds had good inhibitions at the dose
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