质量水平
检测方案
≥99.0% (NT)
mp
167-170 °C
SMILES字符串
[Na+].CC(O)CC([O-])=O
InChI
1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1
InChI key
NBPUSGBJDWCHKC-UHFFFAOYSA-M
应用
(±)-3-羟基丁酸钠已被用于研究,以了解丁酸盐对成纤维细胞生长因子 21(FGF21)的影响,其参与肝脏中的脂肪酸 β-氧化。它可用于制备聚(3-羟基丁酸酯)。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
监管及禁止进口产品
Behavioural pharmacology, 31(4), 322-332 (2020-01-03)
β-hydroxybutyrate, a ketone body metabolite, has been shown to suppress depression-like behavior in rodents. In this study, we examined its antidepressive property in acute and chronic administration modes in mice by using forced swim test and tail suspension test. Results
The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(1), 34-45 (2011-01-07)
GABA depolarizes immature neurons because of a high [Cl(-)](i) and orchestrates giant depolarizing potential (GDP) generation. Zilberter and coworkers (Rheims et al., 2009; Holmgren et al., 2010) showed recently that the ketone body metabolite DL-3-hydroxybutyrate (DL-BHB) (4 mM), lactate (4
Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3.
Diabetes, 61(4), 797-806 (2012)
Novel synthesis of poly (3-hydroxybutyrate).
Macromolecules, 39(13), 4627-4630 (2006)
International journal of molecular sciences, 19(8) (2018-08-04)
The clinical benefit of ketosis has historically and almost exclusively centered on neurological conditions, lending insight into how ketones alter mitochondrial function in neurons. However, there is a gap in our understanding of how ketones influence mitochondria within skeletal muscle
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