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经验公式(希尔记法):
C4H8O3
化学文摘社编号:
分子量:
104.10
UNSPSC Code:
51113400
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-909-6
Beilstein/REAXYS Number:
1720568
MDL number:
产品名称
(R)-3-羟基丁酸, ≥98.0% (T)
InChI key
WHBMMWSBFZVSSR-GSVOUGTGSA-N
InChI
1S/C4H8O3/c1-3(5)2-4(6)7/h3,5H,2H2,1H3,(H,6,7)/t3-/m1/s1
SMILES string
C[C@@H](O)CC(O)=O
assay
≥98.0% (T)
form
solid
optical activity
[α]20/D −25±1°, c = 6% in H2O
mp
49-50 °C (lit.)
functional group
carboxylic acid
hydroxyl
storage temp.
2-8°C
Quality Level
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Application
( R )-3-羟基丁酸可用于与各种羟基烷酸反应制备共聚物。1 也可用于 (3 R ,4 R )-4-乙酰氧基-3-[ [( R )-1-(甲酰氧基)乙基]-2-氮杂环丁酮的制备。2
Other Notes
重要的手性起始材料;通过环状缩醛和醛进行2-, 3-和4-位的对映选择性反应;(R)-β-丁内酯制备。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
D. Seebach et al.
Modern Synthetic Methods, 4, 125-125 (1986)
Journal of the American Chemical Society, 110, 4763-4763 (1988)
A. Griesbech et al.
Helvetica Chimica Acta, 70, 1320-1320 (1987)
J L Hansen et al.
Clinical chemistry, 24(3), 475-479 (1978-03-01)
Methods are described for direct assays of lactate, pyruvate, beta-hydroxybutyrate, and acetoacetate in plasma with the GEMSAEC centrifugal analyzer. The methods for lactate, beta-hydroxybutyrate, and acetoacetate are kinetic and ratiometric, eliminating the need for specimen-blank assays. The pyruvate method is
Sodium-glucose cotransporter 2 inhibitors regulate ketone body metabolism via inter-organ crosstalk.
Jin Hee Kim et al.
Diabetes, obesity & metabolism (2018-11-09)
To investigate sodium-glucose cotransporter 2 inhibitor (SGLT2i)-induced changes in ketogenic enzymes and transporters in normal and diabetic mice models. Normal mice were randomly assigned to receive either vehicle or SGLT2i (25 mg/kg/d by oral gavage) for 7 days. Diabetic mice were treated
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