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Merck
CN

548644

Sigma-Aldrich

亚氨基芪甲酰氯

90%

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About This Item

经验公式(希尔记法):
C15H10ClNO
CAS号:
分子量:
255.70
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

90%

mp

149-153 °C (lit.)

官能团

chloro

SMILES字符串

ClC(=O)N1c2ccccc2C=Cc3ccccc13

InChI

1S/C15H10ClNO/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H

InChI key

APJYHXJGXDPGBA-UHFFFAOYSA-N

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一般描述

Dibenz [b,f]azepine-5-carbonyl chloride or 5H-dibenz [b,f]azepine-5-carbonyl chloride is a tricyclic heterocyclic compound that can be synthesized from 5H-dibenz[ b,f]azepine.

应用

Dibenz [b,f]azepine-5-carbonyl chloride may be used in the preparation of trans-10,11-dibromo-10,11-dihydro-5H-dibenz[b,f]azepine-5-carbonyl chloride via bromination using bromine. It may also be used to prepare urea derivatives, which are potent P2X4 receptor (purinergic receptor) antagonists.

象形图

Corrosion

警示用语:

Danger

危险声明

危险分类

Skin Corr. 1B

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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分析证书(COA)

Lot/Batch Number

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访问文档库

Maoqun Tian et al.
Bioorganic & medicinal chemistry, 22(3), 1077-1088 (2014-01-15)
Antagonists for the P2 receptor subtype P2X4, an ATP-activated cation channel receptor, have potential as novel drugs for the treatment of neuropathic pain and other inflammatory diseases. In the present study, a series of 47 carbamazepine derivatives including 32 novel
Kinetic evidence for rate determination during the nucleophilic step of olefin bromination. The case of 5H-dibenz [b, f] azepine-5-carbonyl chloride.
Bellucci G and Chiappe C.
The Journal of Organic Chemistry, 58(25), 7120-7127 (1993)

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