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Merck
CN

545996

Sigma-Aldrich

L-硒代胱胺基乙酸

95%, for peptide synthesis

别名:

(R,R)-3,3′-二硒基-双(2-氨基丙酸), L-硒代胱氨酸

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About This Item

线性分子式:
CO2HCH(NH2)CH2(Se)2CH2CH(NH2)CO2H
CAS号:
分子量:
334.09
Beilstein:
1969559
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.22

product name

L-硒代胱胺基乙酸, 95%

质量水平

检测方案

95%

形式

powder or crystals

旋光性

[α]20/D −28°, c = 1 in NaOH

反应适用性

reaction type: solution phase peptide synthesis

mp

224.5-229.5 °C (lit.)

应用

peptide synthesis

储存温度

2-8°C

SMILES字符串

N[C@@H](C[Se][Se]C[C@H](N)C(O)=O)C(O)=O

InChI

1S/C6H12N2O4Se2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1

InChI key

JULROCUWKLNBSN-IMJSIDKUSA-N

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应用

硒基-L-胱氨酸可用于以下物质的合成:
  • 生物活性硒醇化合物。
  • 非天然硒化二氨基酸。

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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Andrzej Gawor et al.
Animals : an open access journal from MDPI, 10(5) (2020-05-13)
Identification and quantification of the selenium species in biological tissues is imperative, considering the need to properly understand its metabolism and its importance in various field of sciences, especially nutrition science. Although a number of studies deals with the speciation
Synthesis of novel Se-substituted selenocysteine derivatives as potential kidney selective prodrugs of biologically active selenol compounds: evaluation of kinetics of ?-elimination reactions in rat renal cytosol
Andreadou I, et al.
Journal of Medicinal Chemistry, 39(10), 2040-2046 (1996)
Novel selenium-containing non-natural diamino acids
Caputo R, et al.
Tetrahedron Letters, 48(8), 1425-1427 (2007)
Tianfeng Chen et al.
Journal of agricultural and food chemistry, 56(22), 10574-10581 (2008-10-31)
Selenocystine (SeC) is a nutritionally available selenoamino acid with selective anticancer effects on a number of human cancer cell lines. The present study shows that SeC inhibited the proliferation of human breast adenocarcinoma MCF-7 cells in a time- and dose-dependent
B Santhosh Kumar et al.
Radiation and environmental biophysics, 48(4), 379-384 (2009-09-17)
Organoselenium compounds belonging to the class of monoselenides, such as selenomethionine (SeM) and methylselenocysteine (MSeCys) and diselenides including selenocystine (SeCys) and selenopropionic acid (SePA), were examined for their comparative radioprotective effects using in vitro models. Effects of these compounds on

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