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Merck
CN

545996

Sigma-Aldrich

L-硒代胱胺基乙酸

95%, for peptide synthesis

别名:

(R,R)-3,3′-二硒基-双(2-氨基丙酸), L-硒代胱氨酸

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About This Item

线性分子式:
CO2HCH(NH2)CH2(Se)2CH2CH(NH2)CO2H
CAS号:
分子量:
334.09
Beilstein:
1969559
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.22

产品名称

L-硒代胱胺基乙酸, 95%

质量水平

方案

95%

表单

powder or crystals

旋光性

[α]20/D −28°, c = 1 in NaOH

反应适用性

reaction type: solution phase peptide synthesis

mp

224.5-229.5 °C (lit.)

应用

peptide synthesis

储存温度

2-8°C

SMILES字符串

N[C@@H](C[Se][Se]C[C@H](N)C(O)=O)C(O)=O

InChI

1S/C6H12N2O4Se2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1

InChI key

JULROCUWKLNBSN-IMJSIDKUSA-N

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应用

硒基-L-胱氨酸可用于以下物质的合成:
  • 生物活性硒醇化合物。
  • 非天然硒化二氨基酸。

警示用语:

Danger

危险分类

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Novel selenium-containing non-natural diamino acids
Caputo R, et al.
Tetrahedron Letters, 48(8), 1425-1427 (2007)
Andrzej Gawor et al.
Animals : an open access journal from MDPI, 10(5) (2020-05-13)
Identification and quantification of the selenium species in biological tissues is imperative, considering the need to properly understand its metabolism and its importance in various field of sciences, especially nutrition science. Although a number of studies deals with the speciation
Synthesis of novel Se-substituted selenocysteine derivatives as potential kidney selective prodrugs of biologically active selenol compounds: evaluation of kinetics of ?-elimination reactions in rat renal cytosol
Andreadou I, et al.
Journal of Medicinal Chemistry, 39(10), 2040-2046 (1996)
Amit Kunwar et al.
Radiation and environmental biophysics, 50(2), 271-280 (2011-01-25)
Selenocystine (CysSeSeCys), a diselenide aminoacid exhibiting glutathione peroxidase-like activity and selective antitumor effects, was examined for in vivo antigenotoxic and antioxidant activity in Swiss albino mice after exposure to a sublethal dose (5 Gy) of γ-radiation. For this, CysSeSeCys was administered
Rui Gusmão et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 17(2), 321-329 (2011-10-22)
Selenium-containing compounds play an important role in antioxidant defense systems, binding to toxic metals, preventing their uptake into cells, and thus protecting cells from metal-induced formation of reactive oxygen species. Here, we present a proposal for a relatively new method

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