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Merck
CN

545953

1-氨基海因 盐酸盐

98%

别名:

1-氨基-2,4-咪唑烷二酮 盐酸盐

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关于此项目

经验公式(希尔记法):
C3H5N3O2 · HCl
化学文摘社编号:
分子量:
151.55
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3699376
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产品名称

1-氨基海因 盐酸盐, 98%

InChI

1S/C3H5N3O2.ClH/c4-6-1-2(7)5-3(6)8;/h1,4H2,(H,5,7,8);1H

SMILES string

Cl[H].NN1CC(=O)NC1=O

InChI key

WEOHANUVLKERQI-UHFFFAOYSA-N

assay

98%

mp

201-205 °C (lit.)

Quality Level

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Application

1-氨基乙内酰脲盐酸盐可作为合成 ( E )-1-(2-羟基亚苄基氨基)咪唑烷-2,4-二酮、 丹曲林 和丹曲林钠的反应物之一。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Synthesis of 1-Aminohydantoin Hydrochloride-(2-~(13) C,~(15) N_3) as Double Labeling Compound
Xu JF, et al.
Chemical World, 10, 015-015 (2012)
R L White et al.
Journal of medicinal chemistry, 30(2), 263-266 (1987-02-01)
A series of 1-[[[5-(substituted phenyl)-2-oxazolyl]methylene]amino]- 2,4-imidazolidinediones (6a-t) was synthesized, and the compounds were evaluated for direct skeletal muscle inhibition in the pithed rat gastrocnemius muscle preparation. The correctness of structural assignment of the new series was verified by alternate, unequivocal
William Andrew Publishing et al.
Pharmaceutical Manufacturing Encyclopedia, 1-4, 1193-1193 (2013)
Johann Leban et al.
Bioorganic & medicinal chemistry, 16(8), 4579-4588 (2008-03-04)
Peptide-semicarbazones derived from Z-Trp-Trp-Phe-aldehyde inhibit the chymotryptic activity of the human proteasome at nanomolar concentrations, but are less active in a NFkappaB reporter gene assay. Cyclic semicarbazones, in contrast, combine a strong inhibitory effect on the enzyme with an inhibition
Crystal structure of (E)-1-(2-hydroxybenzylideneamino) imidazolidine-2, 4-dione, C10H9N3O3.
Hu, Lei, et al.
Zeitschrift fur Kristallographie, 230(2), 111-112 (2015)

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