质量水平
检测方案
98%
mp
201-205 °C (lit.)
SMILES字符串
Cl[H].NN1CC(=O)NC1=O
InChI
1S/C3H5N3O2.ClH/c4-6-1-2(7)5-3(6)8;/h1,4H2,(H,5,7,8);1H
InChI key
WEOHANUVLKERQI-UHFFFAOYSA-N
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应用
1-氨基乙内酰脲盐酸盐可作为合成 ( E )-1-(2-羟基亚苄基氨基)咪唑烷-2,4-二酮、 丹曲林 和丹曲林钠的反应物之一。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Bioorganic & medicinal chemistry letters, 18(9), 2840-2844 (2008-04-25)
We report here a class of thiazolidine-2,4-diones and 2-thioxothiazolidin-4-ones as potent inhibitors of the lymphoid specific tyrosine phosphatase (Lyp) identified from high throughput screens. Chemical modification by incorporating the known phosphotyrosine (pTyr) mimics led to the discovery of a salicylate-based
Bioorganic & medicinal chemistry letters, 20(2), 649-652 (2009-12-08)
A series of hydrazonotrifluorosulfonanilide derivatives were synthesized and evaluated for in vitro activity against the ectoparasites Ctenocephalides felis and Rhipicephalus sanguineus. Some compounds with excellent activity against tick were identified.
Pharmaceutical Manufacturing Encyclopedia, 1-4, 1193-1193 (2013)
Journal of medicinal chemistry, 30(2), 263-266 (1987-02-01)
A series of 1-[[[5-(substituted phenyl)-2-oxazolyl]methylene]amino]- 2,4-imidazolidinediones (6a-t) was synthesized, and the compounds were evaluated for direct skeletal muscle inhibition in the pithed rat gastrocnemius muscle preparation. The correctness of structural assignment of the new series was verified by alternate, unequivocal
Crystal structure of (E)-1-(2-hydroxybenzylideneamino) imidazolidine-2, 4-dione, C10H9N3O3.
Zeitschrift fur Kristallographie, 230(2), 111-112 (2015)
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