所有图片(2)
About This Item
经验公式（希尔记法）:
C4H2Cl2O2S2
CAS号:
分子量:
217.09
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
质量水平
检测方案
96%
折射率
n20/D 1.586 (lit.)
bp
112-117 °C (lit.)
密度
1.623 g/mL at 25 °C (lit.)
储存温度
2-8°C
SMILES字符串
Clc1ccc(s1)S(Cl)(=O)=O
InChI
1S/C4H2Cl2O2S2/c5-3-1-2-4(9-3)10(6,7)8/h1-2H
InChI key
SORSTNOXGOXWAO-UHFFFAOYSA-N
一般描述
5-Chlorothiophene-2-sulfonyl chloride can be prepared from 2-chlorothiophene by reacting with chlorosulfonic acid in the presence of phosphorus pentachloride.
应用
5-Chlorothiophene-2-sulfonyl chloride may be used in the preparation of:
- (S)-N-(5-chlorothiophene-2-sulfonyl)-β,β-diethylalaninol
- N-(3-(1H-pyrazol-1-yl)pyridin-2-yl)-5-chlorothiophene-2-sulfonamide
- 5-chloro-4-nitrothiophene-2-sulfonyl chloride
警示用语：
Danger
危险声明
危险分类
Eye Dam. 1 - Skin Corr. 1B
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
C A Hunt et al.
Journal of medicinal chemistry, 37(2), 240-247 (1994-01-21)
3-Aminoalkyl derivatives of thieno[2,3-b][1,4]thiazine-6-sulfonamide were prepared for evaluation as topically active ocular hypotensive agents. The compounds described were found to be excellent in vitro inhibitors of carbonic anhydrase II and in vivo to lower intraocular pressure in three rabbit models
A facile stereoselective total synthesis of (S)-N-(5-chlorothiophene-2-sulfonyl)-?,?-diethylalaninol.
Reddy BN and Sing RP.
Der Pharma Chemica, 7(1), 201-205 (2015)
Afjal H Miah et al.
Organic & biomolecular chemistry, 12(11), 1779-1792 (2014-02-12)
A knowledge-based library of aryl 2,3-dichlorophenylsulfonamides was synthesised and screened as human CCR4 antagonists, in order to identify a suitable hit for the start of a lead-optimisation programme. X-ray diffraction studies were used to identify the pyrazole ring as a
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门