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Merck
CN

540110

Sigma-Aldrich

(2R)-(-)-对甲苯磺酸缩水甘油酯

98%

别名:

(R)-(-)-环氧乙烷-2-甲醇 甲苯磺酸盐, (R)-(-)-缩水甘油基对甲苯磺酸酯, (R)-(-)-缩水甘油基甲苯磺酸酯

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About This Item

经验公式(希尔记法):
C10H12O4S
分子量:
228.26
Beilstein:
3592142
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

98%

mp

46-49 °C (lit.)

储存温度

2-8°C

SMILES字符串

Cc1ccc(cc1)S(=O)(=O)OC[C@H]2CO2

InChI

1S/C10H12O4S/c1-8-2-4-10(5-3-8)15(11,12)14-7-9-6-13-9/h2-5,9H,6-7H2,1H3/t9-/m1/s1

InChI key

NOQXXYIGRPAZJC-SECBINFHSA-N

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应用

(2R)-(-)-Glycidyl tosylate may be used to prepare:
  • 1-O-hexadecyl-sn-glycerol 3-O-p-toluenesulfonate by reacting with 1-hexadecanol in the presence of boron trifluoride etherate.
  • 4-Oxiranylmethoxy-(1H)-indole by reacting with 4-hydroxyindole in the presence of sodium hydride.
  • [18F]Epifluorohydin, an intermediate for preparing of [18F]fluoromisonidazole.
It can also be used as a starting material in the synthesis of 1,2-diacyl-sn-3-glycerophosphocholines.

法律信息

经 Shasun Chemicals and Drugs Limited 授权,使用 Jacobsen HKR 技术制造。

警示用语:

Danger

危险分类

Aquatic Chronic 2 - Carc. 1B - Eye Dam. 1 - Muta. 2 - Skin Sens. 1

WGK

WGK 3

闪点(°F)

>230.0 °F

闪点(°C)

> 110 °C

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


分析证书(COA)

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A Radiosynthesis of fluorine-18.
Grierson JR, et al.
Journal of Nuclear Medicine, 30, 343-350 (1989)
Isosteric phosphonate analogs of ET-16-OMe. Synthesis and biological evaluation of the enantiomers of 2'-(Trimethylammonio) ethyl 4-(hexadecyloxy)-3-methoxybutanephosphonate and 2'-(trimethylammonio) ethyl 4-(hexadecylthio)-3-methoxybutanephosphonate.
Bittman R, et al.
Journal of Medicinal Chemistry, 37(3), 425-430 (1994)
Facile diacylation of glycidyl tosylate. Chiral synthesis of symmetric-chain glycerophospholipids.
Ali S and Bittman R
The Journal of Organic Chemistry, 53(23), 5547-5549 (1988)
Henry, N. et al.
Tetrahedron Letters, 45, 1465-1465 (2004)
Novel aryloxy-8-azabicyclo [3.2. 1] oct-3-enes with 5-HT transporter and 5-HT 1A affinity.
Gilbert AM, et al.
Bioorganic & Medicinal Chemistry Letters, 14(21), 5281-5284 (2004)

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