所有图片(1)
别名:
(S)-α-Glycerol chlorohydrin
线性分子式:
ClCH2CH(OH)CH2OH
CAS号:
分子量:
110.54
Beilstein:
2202929
MDL编号:
UNSPSC代码:
12352101
PubChem化学物质编号:
NACRES:
NA.22
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质量水平
检测方案
97%
光学纯度
ee: 97% (GLC)
折射率
n20/D 1.480 (lit.)
bp
213 °C (lit.)
密度
1.322 g/mL at 25 °C (lit.)
SMILES字符串
OC[C@H](O)CCl
InChI
1S/C3H7ClO2/c4-1-3(6)2-5/h3,5-6H,1-2H2/t3-/m1/s1
InChI key
SSZWWUDQMAHNAQ-GSVOUGTGSA-N
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法律信息
经 Shasun Chemicals and Drugs Limited 授权，使用 Jacobsen HKR 技术制造。
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Eye Dam. 1
WGK
WGK 3
闪点(°F)
235.4 °F
闪点(°C)
113 °C
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
Jing Lu et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 144, 111575-111575 (2020-07-24)
3-chloro-1, 2-propanediol (3-MCPD) is a well-known contaminant that was produced in the thermal processing of food. Dietary intake represents the greatest source of exposure to 3-MCPD. Autophagy is an important catabolic pathway that plays an important role in liver physiological
Brian D Craft et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 29(3), 354-361 (2011-12-16)
Recently, organic and inorganic chlorinated compounds were detected in crude and commercially refined palm oils. Further, the predominant formation mechanism of monochloropropanediol (MCPD) diesters at high temperatures (>170-180°C) was revealed. The present study involved the development and comparison of solutions
Hao Zhang et al.
Wei sheng yan jiu = Journal of hygiene research, 37(2), 133-136 (2008-07-01)
To study the effects of S-alpha-chlorohydrin on male ICR mice mating index, fertility index and the histopathologic changes of testis and epididymis. 64 sexually mature male ICR mice were randomly divided into four groups, each group contained 16 mice. At
Nithar Ranjan Madhu et al.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 30(2), 93-102 (2011-10-05)
To examine the effects of α-chlorohydrin on testis and cauda epididymis in the male house rat (Rattus rattus), 24 adult male rats were segregated into two groups. Group I rats were force-fed daily by intragastric intubation with α-chlorohydrin at a
Shuwu Xie et al.
Reproductive biology and endocrinology : RB&E, 8, 37-37 (2010-04-23)
As one of the chlorinated antifertility compounds, alpha-chlorohydrin (ACH) can inhibit glyceraldehyde-3-phosphate dehydrogenase (G3PDH) activity in epididymal sperm and affect sperm energy metabolism, maturation and fertilization, eventually leading to male infertility. Further studies demonstrated that the inhibitory effect of ACH
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