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质量水平
检测方案
≥99.0% (AT)
形式
solid
缺失
≤0.5% loss on drying
mp
202 °C (dec.) (lit.)
~203 °C (dec.)
SMILES字符串
Cl[H].NC1CCSC1=O
InChI
1S/C4H7NOS.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H
InChI key
ZSEGSUBKDDEALH-UHFFFAOYSA-N
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一般描述
DL-高半胱氨酸硫代内酯盐酸盐（HTL-HCl）是一种环状氨基酸衍生物，具有根生长抑制活性。
应用
DL-同型半胱氨酸硫代内酯盐酸盐可用于制备：
- DL-丁硫氨酸
- DL-同型半胱氨酸
- 聚[α,β-(N-2-氨基乙基-dl-天冬酰胺)]-聚[α,β-(N-2-羟乙基-dl-天冬酰胺)]-聚[α,β-(N-3-巯基-1-甲氧基羰基-丙基-dl-天冬酰胺)]共聚物双氯芬酸偶联物（PAHMA-Dic）
- 双[ S-(二甲基胂基)高半胱氨酸]
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
O W Griffith et al.
The Journal of biological chemistry, 254(16), 7558-7560 (1979-08-25)
Buthionine sulfoximine (S-n-butyl homocysteine sulfoximine), the most potent of a series of analogs of methionine sulfoximine thus far studied (Griffith, O.W., Anderson, M.E., and Meister, A. (1979) J. Biol. Chem. 254, 1205-1210), inhibited gamma-glutamylcysteine synthetase about 20 times more effectively
Root-growth inhibition by DL-homocysteine thiolactone and its related compounds.
Inamori Y, et al.
Bioscience, Biotechnology, and Biochemistry, 59(3), 523-525 (1995)
Kotchakorn Juntapram et al.
Carbohydrate polymers, 90(4), 1469-1479 (2012-09-05)
Novel hydrogel polyelectrolyte complexes (PECs) between the N,N,N,-trimethylchitosan-homocysteine thiolactone (TM-HT-chitosan) and two anionic polymers were investigated. The particles of pure thiolated chitosan and its PECs with alginate and carrageenan were fabricated using the electrospray ionization technique. The hydrogel PEC particles
Joanna Malinowska et al.
Nutrition (Burbank, Los Angeles County, Calif.), 28(7-8), 793-798 (2012-01-21)
Aronia melanocarpa fruits (Rosaceae) are one of the richest plant sources of phenolic substances, and it has been shown to have various biological activities. Berries of A. melanocarpa (chokeberry) have been supposed to be beneficial for the prevention of cardiovascular
Hieronim Jakubowski et al.
Advances in clinical chemistry, 55, 81-103 (2011-12-01)
Protein-related homocysteine (Hcy) metabolism produces Hcy-thiolactone, N-Hcy-protein, and N epsilon-homocysteinyl-lysine (N epsilon-Hcy-Lys). Hcy-thiolactone is generated in an error-editing reaction in protein biosynthesis when Hcy is erroneously selected in place of methionine by methionyl-tRNA synthetase. Hcy-thiolactone, an intramolecular thioester, is chemically
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