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Merck
CN

533084

6-甲氧基-2-萘醛

98%

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线性分子式:
CH3OC10H6CHO
化学文摘社编号:
分子量:
186.21
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
222-377-2
MDL number:
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产品名称

6-甲氧基-2-萘醛, 98%

InChI key

VZBLASFLFFMMCM-UHFFFAOYSA-N

InChI

1S/C12H10O2/c1-14-12-5-4-10-6-9(8-13)2-3-11(10)7-12/h2-8H,1H3

SMILES string

COc1ccc2cc(C=O)ccc2c1

assay

98%

mp

81-84 °C (lit.)

functional group

aldehyde

Quality Level

Application

6-甲氧基-2-萘乙醛可用于制备以下与 4-(6-甲氧基-2-萘基)丁-2-相关的化合物:
  • 4-(6-甲氧基-2-萘基)but-3-en-2-酮
  • 4-(6-甲氧基-2-萘基)-3-甲基丁-2-酮
  • 5-(6-甲氧基-2-萘基)戊三-3-酮

它也可以用于合成以下查尔酮衍生物:
  • (2E)-1-(2-羟基苯基)-3-(6-甲氧基-2-萘基)prop-2-en-1-酮
  • E)-1-(2-氯吡啶-4-基)-3-(6-甲氧基-2-萘基)丙-2-烯-1-酮
  • E)-3-(6-甲氧基-2-萘基)-1-吡啶-4-基丙-2-烯-1-酮
  • (2E)-1-(2,4-二氯苯基)-3-(6-甲氧基-2-萘基)丙-2-烯-1-酮

General description

6-甲氧基-2-萘醛可以通过 2-溴 6-甲氧基萘与原甲酸三乙酯发生格氏反应而制备 。它的晶体属于正交晶体空间群 P212121,并具有出色的 NLO(非线性光学)特性。

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

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4-(6-Methoxy-2-naphthyl) butan-2-one and related analogs, a novel structural class of antiinflammatory compounds.
Goudie AC, et al.
Journal of Medicinal Chemistry, 21(12), 1260-1264 (1978)
Hina Younus et al.
Chemosphere, 243, 125358-125358 (2019-11-24)
Human salivary aldehyde dehydrogenase (hsALDH) is an important detoxifying enzyme and maintains oral health. Subjects with low hsALDH activity are at a risk of developing oral cancers. Arsenic (As) toxicity causes many health problems in humans. The objective of this
J Wierzchowski et al.
Analytical biochemistry, 245(1), 69-78 (1997-02-01)
Two highly fluorogenic aldehydes, 7-methoxy-1-naphthaldehyde (MONAL-71) and 6-methoxy-2-naphthaldehyde (MONAL-62), were examined as indicators of the aldehyde dehydrogenase (ALDH) activity in human tissue homogenates and accessible body fluids. Both compounds were previously found to be excellent substrates for the ALDH from
Structures of three chalcones derived from 6-Methoxy-2-naphthaldehyde.
Jasinski JP, et al.
Journal of Chemical Crystallography, 39(3), 157-162 (2009)
Md Fazle Alam et al.
PloS one, 11(12), e0168463-e0168463 (2016-12-21)
Cruciferous vegetables contain the bio-active compound sulforaphane (SF) which has been reported to protect individuals against various diseases by a number of mechanisms, including activation of the phase II detoxification enzymes. In this study, we show that the extracts of

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