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Merck
CN

532363

Sigma-Aldrich

(S)-(-)-1,2-环氧丁烷

98%

别名:

(2S)-乙基环氧乙烷

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About This Item

经验公式(希尔记法):
C4H8O
CAS号:
分子量:
72.11
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

98%

旋光性

[α]20/D −10°, neat

折射率

n20/D 1.386 (lit.)

沸点

63 °C (lit.)

密度

0.837 g/mL at 25 °C (lit.)

官能团

ether

SMILES字符串

CC[C@H]1CO1

InChI

1S/C4H8O/c1-2-4-3-5-4/h4H,2-3H2,1H3/t4-/m0/s1

InChI key

RBACIKXCRWGCBB-BYPYZUCNSA-N

应用

(S)-(−)-1,2-Epoxybutane can be used:
  • As a starting material to prepare (+)- and (−)-homononactic acids, which are used as intermediates in the total synthesis of a cyclic antibiotic tetranactin.
  • To prepare a chiral phosphorus synthon, which is applicable in the synthesis of phytoprostane B1 type I.
  • To prepare Eu3+-based precatalysts applicable in the Mukaiyama Aldol reaction in water.

法律信息

经 Shasun Chemicals and Drugs Limited 授权,使用 Jacobsen HKR 技术制造。

警示用语:

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

10.0 °F - closed cup

闪点(°C)

-12.2 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles

法规信息

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分析证书(COA)

Lot/Batch Number

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A flexible synthesis of the phytoprostanes B1 type I and II
El Fangour S, et al.
The Journal of Organic Chemistry, 70(3), 989-997 (2005)
Synthesis of (+)-and (−)-homononactic acid from (S)-1, 2-epoxybutane. Total synthesis of tetranactin by ′reverse coupe du roi′
Schmidt U and Werner J
Journal of the Chemical Society. Chemical Communications, 996-998 (1986)
Synthesis, spectroscopic characterization, and reactivity of water-tolerant Eu3+-based precatalysts
Averill DJ and Allen MJ
Inorganic Chemistry, 53(12), 6257-6263 (2014)
M Katz et al.
Journal of environmental pathology and toxicology, 3(5-6), 171-187 (1980-06-01)
Nitrosopiperidine, sodium nitrite and 1,2 epoxybutane were tested in the Ames agar incorporation assay in an attempt to establish exact criteria for detecting the activity of these weak mutagens. As regards minimum concentrations it was determined that at 500 microgram
Hong Yuan Sun et al.
Carbohydrate research, 344(15), 1999-2004 (2009-08-26)
A new soluble cyclodextrin derivative 6-O-(2-hydroxybutyl)-beta-cyclodextrin (6-HB-beta-CD) was prepared. Its molecular binding and recognition ability were investigated with the comparison of beta-cyclodextrin (beta-CD), 2-O-(2-hydroxypropyl)-beta-cyclodextrin (2-HP-beta-CD), 6-O-(2-hydroxypropyl)-beta-cyclodextrin (6-HP-beta-CD), and 2-O-(2-hydroxybutyl)-beta-cyclodextrin (2-HB-beta-CD). The relationship between the complex stability constants and the possible

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