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方案
98%
旋光性
[α]20/D −8.0°, c = 2% in acetic acid
mp
242-245 °C (lit.)
SMILES字符串
Cn1cc(C[C@H](N)C(O)=O)c2ccccc12
InChI
1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m0/s1
InChI key
ZADWXFSZEAPBJS-JTQLQIEISA-N
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Itzel Y Rojas et al.
Obesity (Silver Spring, Md.), 29(2), 337-349 (2021-01-26)
The aryl hydrocarbon receptor (AHR) plays a key role in obesity. In vitro studies revealed that the tryptophan metabolite kynurenine (Kyn) activates AHR signaling in cultured hepatocytes. The objective of this study was to determine whether Kyn activated the AHR
Itzel Y Rojas et al.
International journal of obesity (2005), 44(4), 948-963 (2020-01-09)
Obesity is a global epidemic and the underlying basis for numerous comorbidities. We report that the aryl hydrocarbon receptor (AHR) plays a key role in the metabolism of obesity. The AHR is a promiscuous, ligand-activated nuclear receptor primarily known for
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