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检测方案
97%
mp
43-48 °C (lit.)
储存温度
2-8°C
SMILES字符串
COc1ccc(C=O)c(F)c1
InChI
1S/C8H7FO2/c1-11-7-3-2-6(5-10)8(9)4-7/h2-5H,1H3
InChI key
UNWQNFJBBWXFBG-UHFFFAOYSA-N
一般描述
2-Fluoro-4-methoxybenzaldehyde is a fluorinated aromatic aldehyde. It can be prepared from 4-bromo-3-fluoroanisole.
应用
2-Fluoro-4-methoxybenzaldehyde may be used in the preparation of:
- fluorine containing 2,4,5-trisubstituted imidazole
- 1-(2-fluoro-4-methoxyphenyl)-2-propanone
- 6-(2-fluoro-4-methoxyphenyl)fulvene
- 10-(2-fluoro-4-methoxyphenyl)-6,7,9,10-tetrahydro-1Hfuro[3,4-b]pyrazolo[3,4-f]quinolin-9-one
- polyhydroquinoline (PHQ)
- 3-(2-fluoro-4-methoxyphenyl) acrylic acid methyl ester
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
Fluorinated derivatives of titanocene Y: synthesis and cytotoxicity studies.
Claffey J, et al.
European Journal of Organic Chemistry, 26, 4074-4082 (2008)
Indium trifluoride: A highly efficient catalyst for the synthesis of fluorine-containing 2, 4, 5-trisubstituted imidazoles under solvent-free conditions.
Reddy MV and Jeong YT.
Journal of Fluorine Chemistry, 142, 45-51 (2012)
Jack G Parsons et al.
Molecules (Basel, Switzerland), 9(6), 449-458 (2007-11-17)
The synthesis of (2S)-2-benzyloxymethyl-3-(2-fluoro-4-methoxyphenyl)- propionic acid, (2S)-2-benzyloxymethyl-3-(2-fluoro-4-methylphenyl)propionic acid and (2S)-2-benzyl-oxymethyl-3-(2,4-dimethylphenyl)propionic acid has been achieved by TiCl4 mediated alkylation of the corresponding (4R)-4-benzyl-3-[3-(2-fluoro-4-methoxyphenyl-, 2-fluoro-4-methylphenyl-, 2,4- dimethylphenyl-)propionyl]-2-oxazolidinones, followed by hydrolysis of the chiral auxiliary. The stereochemistry of the alkylation reaction was confirmed
Synthesis of 1, 3-Bis (hydroxy-halogenophenyl)-propane-1, 3-diamines and their Pt (II) Complexes, Syntheses of the Ligands.
Kammermeier T and Wiegrebe W.
Arch. Pharm. (Weinheim), 327, 547-561 (1994)
Polystyrene-Supported p-Toluenesulfonic Acid: A New, Highly Efficient, and Recyclable Catalyst for the Synthesis of Hydropyridine Derivatives under Solvent-Free Conditions.
Reddy MV and Jeong YT.
Synlett, 23(20), 2985-2991 (2012)
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