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Merck
CN

528099

Sigma-Aldrich

8-氨基-6-甲氧基喹啉氢溴酸盐

97%

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经验公式(希尔记法):
C10H10N2O · HBr
分子量:
255.11
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

检测方案

97%

mp

238 °C (dec.) (lit.)

SMILES字符串

Br.COc1cc(N)c2ncccc2c1

InChI

1S/C10H10N2O.BrH/c1-13-8-5-7-3-2-4-12-10(7)9(11)6-8;/h2-6H,11H2,1H3;1H

InChI key

WGYQQCWLZRGIKB-UHFFFAOYSA-N

一般描述

8-Amino-6-methoxyquinoline hydrobromide is a quinoline building block. It is formed during the synthesis of α-morpholino-β-(N-8-amino-6-methoxyquinoline)-benzylacetophenone.

应用

8-Amino-6-methoxyquinoline hydrobromide may be used as an amino component in a novel series of bladder-selective diaminocyclobutenedione potassium channel openers. It may also be used for the synthesis of 1-N-(6-methoxy-8-quinoyl)-4′-carboxyl-benzensulfonamide.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Iris Boll et al.
Bioorganic & medicinal chemistry letters, 16(10), 2781-2785 (2006-02-24)
Two ligand-intercalator-peptide nucleic acid conjugates (L-NADI-PNAs) have been synthesized. Affinity of these conjugates to their complementary DNAs was found to be affected by Zn(2+). The magnitude of this effect could be controlled by a variation of the ligand. Upon binding
Butera JA.
Journal of Medicinal Chemistry, 43, 1187-1187 (2000)
Armer RE, et al.
Bioorganic & Medicinal Chemistry, 9, 2430-2430 (1999)
a, ?-Diamino Ketones. III. 1 Reaction of 8-Amino-6-methoxyquinoline with a-Bromo-?-aminoketones.
Cromwell NH and Hoeksema H.
Journal of the American Chemical Society, 67(1), 124-125 (1945)

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