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质量水平
方案
96%
表单
solid
mp
265 °C (dec.) (lit.)
官能团
hydroxyl
SMILES字符串
N[C@]12C[C@@H]3C[C@H](C1)C[C@@](O)(C3)C2
InChI
1S/C10H17NO/c11-9-2-7-1-8(3-9)5-10(12,4-7)6-9/h7-8,12H,1-6,11H2/t7-,8+,9+,10-
InChI key
DWPIPTNBOVJYAD-FIRGSJFUSA-N
应用
用于合成具有抗高血糖特性的抑制剂。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
230.0 °F - closed cup
闪点(°C)
110 °C - closed cup
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Nieves Fresno et al.
PloS one, 9(12), e113841-e113841 (2014-12-02)
Paracetamol also known as acetaminophen, is a widely used analgesic and antipyretic agent. We report the synthesis and biological evaluation of adamantyl analogues of paracetamol with important analgesic properties. The mechanism of nociception of compound 6a/b, an analog of paracetamol
NOVEL TRICYCLIC CYANOPYRROLIDINE DERIVATIVES AS DPP4 INHIBITORS: AN IMPROVED SYNTHESIS OF TRICYCLIC a-CYCNOPYRROLIDINE FROM CAMPHOR.
Arumugam K and Anitha M.
Rasayan Journal of Chemistry, 6(3), 230-237 (2013)
Further calculations on solubility of 3-amino-1-adamantanol in ethanol+ water binary solvent mixtures at various temperatures.
Jouyban A, et al.
Journal of Molecular Liquids, 219, 211-215 (2016)
Ramzia I El-Bagary et al.
International journal of biomedical science : IJBS, 7(3), 201-208 (2011-09-01)
Two reversed-phase liquid chromatographic (RP-LC) methods are described for the determination of two binary mixtures of hypoglycemic agents. In the first method, vildagliptin (VDG) was determined in the presence of 3-amino-1-adamantanol (AAD), a synthetic intermediate and impurity of VDG. In
A Facile and Economical Method to Synthesize Vildagliptin.
Deng Y, et al.
Letters in Organic Chemistry, 11(10), 780-784 (2014)
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