所有图片(1)
About This Item
经验公式（希尔记法）:
C6H4F3N
CAS号:
分子量:
147.10
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
质量水平
检测方案
97%
折射率
n20/D 1.417 (lit.)
bp
110 °C (lit.)
密度
1.27 g/mL at 25 °C (lit.)
SMILES字符串
FC(F)(F)c1ccncc1
InChI
1S/C6H4F3N/c7-6(8,9)5-1-3-10-4-2-5/h1-4H
InChI key
IIYVNMXPYWIJBL-UHFFFAOYSA-N
一般描述
4-（三氟甲基）吡啶是吡啶衍生物。它可以通过 4-碘苯的三氟甲基化来制备。
应用
4-（三氟甲基）吡啶可用于以下反应：
- 通过金属化反应制备（三氟甲基）吡啶基锂。
- 金属有机骨架（MOF）的合成。
- 甲硫氰酸盐的合成。
警示用语：
Danger
危险分类
Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
closed cup
闪点(°C)
closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
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Journal of Materials Chemistry, 19(15), 2131-2134 (2009)
Fluorinated pyridine derivatives: Part 1. The synthesis of some mono-and bis-quaternary pyridine salts of potential use in the treatment of nerve agent poisoning.
Timperley CM, et al.
Journal of Fluorine Chemistry, 126(8), 1160-1165 (2005)
Manfred Schlosser et al.
Chemical Society reviews, 36(7), 1161-1172 (2007-06-20)
Pyridines carrying heterosubstituents (such as carboxy, amido, amino, alkoxy or trifluoromethyl groups or solely individual halogen atoms) can be readily and site selectively metalated. Subsequent reaction with a suitable electrophile opens rational access to a wealth of new building blocks
Copper-mediated trifluoromethylation of heteroaromatic compounds by trifluoromethyl sulfonium salts.
Cheng-Pan Zhang et al.
Angewandte Chemie (International ed. in English), 50(8), 1896-1900 (2011-02-18)
Joonhyuck Park et al.
ACS nano, 14(9), 11579-11593 (2020-08-14)
A heat-up method for quantum dots (QDs) synthesis holds distinctive benefits for large-scale production with its simplicity, scalability, and high reproducibility. Its applications, however, have been limited because it inevitably yields a strong overlap between the nucleation and the growth
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