跳转至内容
Merck
CN
所有图片(1)

文件

安全信息

498181

Sigma-Aldrich

2-氯-5-碘吡啶

97%

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C5H3ClIN
CAS号:
69045-79-0
分子量:
239.44
MDL编号:
MFCD01863635
UNSPSC代码:
12352100
PubChem化学物质编号:
24873177
NACRES:
NA.22

质量水平

100

检测方案

97%

mp

95-98 °C (lit.)

SMILES字符串

Clc1ccc(I)cn1

InChI

1S/C5H3ClIN/c6-5-2-1-4(7)3-8-5/h1-3H

InChI key

QWLGCWXSNYKKDO-UHFFFAOYSA-N

相关类别

一般描述

2-Chloro-5-iodopyridine is a halo-substituted pyridine.

应用

2-Chloro-5-iodopyridine may be used as a reagent in the multi-step synthesis of (±)-epibatidine.
It may be used in the synthesis of:
  • 2-Chloro-5-phenylpyridine via Suzuki coupling reaction with phenylboronic acid dimethyl ester.
  • Exo-5- and exo-6- (6′-chloro-3′-pyridyl)-2-azabicyclo[2.2.1]heptanes via Heck coupling reaction with N-protected 2-azabicyclo[2.2.1]hept-5-enes.
  • Substituted diaryliodonium salts.
  • 3-Exo-5′-(2′-Chloropyridinyl)-8-(ethoxycarbonyl)-8-azabicyclo[3.2.1]octane.

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319,H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

High-yielding one-pot synthesis of diaryliodonium triflates from arenes and iodine or aryl iodides.
Bielawski M and Olofsson B
Chemical Communications (Cambridge, England), 24, 2521-2523 (2007)
Synthesis of epibatidine isomers: Reductive Heck coupling of 2-azabicyclo [2.2.1] hept-5-ene derivatives.
Cox CD and Malpass JR
Tetrahedron, 55(40), 11879-11888 (1999)
Syntheses of new open-ring and homo-epibatidine analogues from tropinone.
Olivo HF, et al.
The Journal of Organic Chemistry, 64(13), 4966-4968 (1999)
A short and efficient total synthesis of (?)-epibatidine.
A short and efficient total synthesis of (?)-epibatidine.
Zhang C and Trudell ML.
The Journal of Organic Chemistry, 61(20), 7189-7191 (1996)
Synthesis of 5-Substituted 2,2'-Bipyridines from Substituted 2-Chloropyridines by a Modified Negishi Cross-Coupling Reaction.
Lutzen A and Hapke M.
European Journal of Organic Chemistry, 2002(14), 2292-2297 (2002)

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门